Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: Applications in ratiometric oxygen sensing in vitro and in regioselective cell killing

Ga Lai Law; Robert Pal; Lars O. Palsson; David Parker; Ka Leung Wong

doi:10.1039/b920222f

Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: Applications in ratiometric oxygen sensing in vitro and in regioselective cell killing

Ga Lai Law, Robert Pal, Lars O. Palsson, David Parker, Ka Leung Wong

Research output: Journal article publication › Journal article › Academic research › peer-review

111 Citations (Scopus)

Abstract

A terbium complex has been designed that may be used to sensitise formation of singlet oxygen (em12%), allowing the creation of a ratiometric sensory system for pO2(versus the insensitive Eu analogue) and the definition of a reactive probe that can be used to cause local damage to cells loaded with the complex and exposed to laser excitation.

Original language	English
Pages (from-to)	7321-7323
Number of pages	3
Journal	Chemical Communications
Issue number	47
DOIs	https://doi.org/10.1039/b920222f
Publication status	Published - 30 Dec 2009
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b920222f

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abstract = "A terbium complex has been designed that may be used to sensitise formation of singlet oxygen (em12%), allowing the creation of a ratiometric sensory system for pO2(versus the insensitive Eu analogue) and the definition of a reactive probe that can be used to cause local damage to cells loaded with the complex and exposed to laser excitation.",

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Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: Applications in ratiometric oxygen sensing in vitro and in regioselective cell killing. / Law, Ga Lai; Pal, Robert; Palsson, Lars O. et al.
In: Chemical Communications, No. 47, 30.12.2009, p. 7321-7323.

Research output: Journal article publication › Journal article › Academic research › peer-review

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AU - Pal, Robert

AU - Palsson, Lars O.

AU - Parker, David

AU - Wong, Ka Leung

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AB - A terbium complex has been designed that may be used to sensitise formation of singlet oxygen (em12%), allowing the creation of a ratiometric sensory system for pO2(versus the insensitive Eu analogue) and the definition of a reactive probe that can be used to cause local damage to cells loaded with the complex and exposed to laser excitation.

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Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: Applications in ratiometric oxygen sensing in vitro and in regioselective cell killing

Abstract

ASJC Scopus subject areas

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