Research on imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS), Academia Sinica

Hui Chen Tsai; Chun Fang Chang; Bi Chang Chen; Ji Yen Cheng; Chih Wei Chu; Hsieh Cheng Han; Koji Hatanaka; Tung Han Hsieh; Chau Hwang Lee; Jung Hsin Lin; Yi Chung Tung; Pei Kuen Wei; Fu Liang Yang; Din Ping Tsai

doi:10.1117/12.2199475

Research on imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS), Academia Sinica

Hui Chen Tsai, Chun Fang Chang, Bi Chang Chen, Ji Yen Cheng, Chih Wei Chu, Hsieh Cheng Han, Koji Hatanaka, Tung Han Hsieh, Chau Hwang Lee, Jung Hsin Lin, Yi Chung Tung, Pei Kuen Wei, Fu Liang Yang, Din Ping Tsai

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

Abstract

Development of imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS) of Academia Sinica in Taiwan is progressing rapidly. The research on advanced lattice light sheet microscopy for temporal visualization of cells in three dimensions at sub-cellular resolution shows novel imaging results. Label-free observation on filopodial dynamics provides a convenient assay on cancer cell motility. The newly-developed software enables us to track the movement of two types of particles through different channels and reconstruct the co-localized tracks. Surface plasmon resonance (SPR) for detecting urinary microRNA for diagnosis of acute kidney injury demonstrates excellent sensitivity. A fully automated and integrated portable reader was constructed as a home-based surveillance system for post-operation hepatocellular carcinoma. New microfluidic cell culture devices for fast and accurate characterizations prove various diagnosis capabilities.

Original language	English
Title of host publication	Biophotonics Japan 2015
Editors	Takashige Omatsu, Yasuyuki Ozeki, Seigo Ohno, Yoshio Hayasaki, Yusuke Ogura
Publisher	SPIE
ISBN (Electronic)	9781510600270
DOIs	https://doi.org/10.1117/12.2199475
Publication status	Published - Oct 2015
Externally published	Yes
Event	Biophotonics Japan 2015 - Tokyo, Japan Duration: 27 Oct 2015 → 28 Oct 2015

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	9792
ISSN (Print)	1605-7422

Conference

Conference	Biophotonics Japan 2015
Country/Territory	Japan
City	Tokyo
Period	27/10/15 → 28/10/15

Keywords

Cell imaging
lattice light sheet microscopy
microfluidic cell culture devices
sensing technology
surface plasmon resonance

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Biomaterials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

More information

10.1117/12.2199475

Cite this

Tsai, H. C., Chang, C. F., Chen, B. C., Cheng, J. Y., Chu, C. W., Han, H. C., Hatanaka, K., Hsieh, T. H., Lee, C. H., Lin, J. H., Tung, Y. C., Wei, P. K., Yang, F. L., & Tsai, D. P. (2015). Research on imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS), Academia Sinica. In T. Omatsu, Y. Ozeki, S. Ohno, Y. Hayasaki, & Y. Ogura (Eds.), Biophotonics Japan 2015 Article 979212 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9792). SPIE. https://doi.org/10.1117/12.2199475

Tsai, Hui Chen ; Chang, Chun Fang ; Chen, Bi Chang et al. / Research on imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS), Academia Sinica. Biophotonics Japan 2015. editor / Takashige Omatsu ; Yasuyuki Ozeki ; Seigo Ohno ; Yoshio Hayasaki ; Yusuke Ogura. SPIE, 2015. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).

@inproceedings{b15a14c666094c118f407048fffbea8e,

title = "Research on imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS), Academia Sinica",

abstract = "Development of imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS) of Academia Sinica in Taiwan is progressing rapidly. The research on advanced lattice light sheet microscopy for temporal visualization of cells in three dimensions at sub-cellular resolution shows novel imaging results. Label-free observation on filopodial dynamics provides a convenient assay on cancer cell motility. The newly-developed software enables us to track the movement of two types of particles through different channels and reconstruct the co-localized tracks. Surface plasmon resonance (SPR) for detecting urinary microRNA for diagnosis of acute kidney injury demonstrates excellent sensitivity. A fully automated and integrated portable reader was constructed as a home-based surveillance system for post-operation hepatocellular carcinoma. New microfluidic cell culture devices for fast and accurate characterizations prove various diagnosis capabilities.",

keywords = "Cell imaging, lattice light sheet microscopy, microfluidic cell culture devices, sensing technology, surface plasmon resonance",

author = "Tsai, {Hui Chen} and Chang, {Chun Fang} and Chen, {Bi Chang} and Cheng, {Ji Yen} and Chu, {Chih Wei} and Han, {Hsieh Cheng} and Koji Hatanaka and Hsieh, {Tung Han} and Lee, {Chau Hwang} and Lin, {Jung Hsin} and Tung, {Yi Chung} and Wei, {Pei Kuen} and Yang, {Fu Liang} and Tsai, {Din Ping}",

year = "2015",

month = oct,

doi = "10.1117/12.2199475",

language = "English",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

publisher = "SPIE",

editor = "Takashige Omatsu and Yasuyuki Ozeki and Seigo Ohno and Yoshio Hayasaki and Yusuke Ogura",

booktitle = "Biophotonics Japan 2015",

address = "United States",

note = "Biophotonics Japan 2015 ; Conference date: 27-10-2015 Through 28-10-2015",

}

Tsai, HC, Chang, CF, Chen, BC, Cheng, JY, Chu, CW, Han, HC, Hatanaka, K, Hsieh, TH, Lee, CH, Lin, JH, Tung, YC, Wei, PK, Yang, FL & Tsai, DP 2015, Research on imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS), Academia Sinica. in T Omatsu, Y Ozeki, S Ohno, Y Hayasaki & Y Ogura (eds), Biophotonics Japan 2015., 979212, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 9792, SPIE, Biophotonics Japan 2015, Tokyo, Japan, 27/10/15. https://doi.org/10.1117/12.2199475

Research on imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS), Academia Sinica. / Tsai, Hui Chen; Chang, Chun Fang; Chen, Bi Chang et al.
Biophotonics Japan 2015. ed. / Takashige Omatsu; Yasuyuki Ozeki; Seigo Ohno; Yoshio Hayasaki; Yusuke Ogura. SPIE, 2015. 979212 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9792).

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

TY - GEN

T1 - Research on imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS), Academia Sinica

AU - Tsai, Hui Chen

AU - Chang, Chun Fang

AU - Chen, Bi Chang

AU - Cheng, Ji Yen

AU - Chu, Chih Wei

AU - Han, Hsieh Cheng

AU - Hatanaka, Koji

AU - Hsieh, Tung Han

AU - Lee, Chau Hwang

AU - Lin, Jung Hsin

AU - Tung, Yi Chung

AU - Wei, Pei Kuen

AU - Yang, Fu Liang

AU - Tsai, Din Ping

PY - 2015/10

Y1 - 2015/10

N2 - Development of imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS) of Academia Sinica in Taiwan is progressing rapidly. The research on advanced lattice light sheet microscopy for temporal visualization of cells in three dimensions at sub-cellular resolution shows novel imaging results. Label-free observation on filopodial dynamics provides a convenient assay on cancer cell motility. The newly-developed software enables us to track the movement of two types of particles through different channels and reconstruct the co-localized tracks. Surface plasmon resonance (SPR) for detecting urinary microRNA for diagnosis of acute kidney injury demonstrates excellent sensitivity. A fully automated and integrated portable reader was constructed as a home-based surveillance system for post-operation hepatocellular carcinoma. New microfluidic cell culture devices for fast and accurate characterizations prove various diagnosis capabilities.

AB - Development of imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS) of Academia Sinica in Taiwan is progressing rapidly. The research on advanced lattice light sheet microscopy for temporal visualization of cells in three dimensions at sub-cellular resolution shows novel imaging results. Label-free observation on filopodial dynamics provides a convenient assay on cancer cell motility. The newly-developed software enables us to track the movement of two types of particles through different channels and reconstruct the co-localized tracks. Surface plasmon resonance (SPR) for detecting urinary microRNA for diagnosis of acute kidney injury demonstrates excellent sensitivity. A fully automated and integrated portable reader was constructed as a home-based surveillance system for post-operation hepatocellular carcinoma. New microfluidic cell culture devices for fast and accurate characterizations prove various diagnosis capabilities.

KW - Cell imaging

KW - lattice light sheet microscopy

KW - microfluidic cell culture devices

KW - sensing technology

KW - surface plasmon resonance

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U2 - 10.1117/12.2199475

DO - 10.1117/12.2199475

M3 - Conference article published in proceeding or book

AN - SCOPUS:84958602802

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Biophotonics Japan 2015

A2 - Omatsu, Takashige

A2 - Ozeki, Yasuyuki

A2 - Ohno, Seigo

A2 - Hayasaki, Yoshio

A2 - Ogura, Yusuke

PB - SPIE

T2 - Biophotonics Japan 2015

Y2 - 27 October 2015 through 28 October 2015

ER -

Tsai HC, Chang CF, Chen BC, Cheng JY, Chu CW, Han HC et al. Research on imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS), Academia Sinica. In Omatsu T, Ozeki Y, Ohno S, Hayasaki Y, Ogura Y, editors, Biophotonics Japan 2015. SPIE. 2015. 979212. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2199475

Research on imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS), Academia Sinica

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

UN SDGs

More information

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