Recent advances of iridium(III) metallophosphors for health-related applications

Po Yu Ho, Cheuk Lam Ho (Corresponding Author), Wai Yeung Wong (Corresponding Author)

Research output: Journal article publicationReview articleAcademic researchpeer-review

47 Citations (Scopus)


Phosphorescent transition metal complexes have been intensively investigated, since these luminophores are distinctively different from fluorescent chromophores in terms of the nature and lifetime scale of photoluminescence (PL). Owing to the inherent differences in the light emission, these metal complexes have been successfully exploited for a variety of optical applications, and some of the studies revealed that phosphorescence is fundamentally important to the experimental results and target performances. Encouragingly, cyclometalated iridium(III) complex is one of the rare entities which shows great potential in various biological and analytical applications, such as luminescent assays, cellular imaging, in vivo imaging and even theranostics. This review article collects the most recent papers on health-related applications by exploiting phosphorescent cyclometalated Ir(III) complexes. At the same time, the structure–property relationships of these Ir(III) complexes will be emphasized throughout the article.

Original languageEnglish
Article number213267
JournalCoordination Chemistry Reviews
Publication statusPublished - 15 Jun 2020


  • Anticancer agent
  • Bioimaging
  • Cyclometalated complex
  • Luminescent assay
  • Phosphorescence
  • Photodynamic therapy

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry
  • Materials Chemistry

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