Recent advances of cellular stimulation with triboelectric nanogenerators

Xingyu Zhou, Gaocai Li, Di Wu, Huaizhen Liang, Weifeng Zhang, Lingli Zeng, Qianqian Zhu, Puxiang Lai, Zhen Wen, Cao Yang, Yue Pan (Corresponding Author)

Research output: Journal article publicationReview articleAcademic researchpeer-review

8 Citations (Scopus)

Abstract

Triboelectric nanogenerators (TENGs) are new energy collection devices that have the characteristics of high efficiency, low cost, miniaturization capability, and convenient manufacture. TENGs mainly utilize the triboelectric effect to obtain mechanical energy from organisms or the environment, and this mechanical energy is then converted into and output as electrical energy. Bioelectricity is a phenomenon that widely exists in various cellular processes, including cell proliferation, senescence, apoptosis, as well as adjacent cells’ communication and coordination. Therefore, based on these features, TENGs can be applied in organisms to collect energy and output electrical stimulation to act on cells, changing their activities and thereby playing a role in regulating cellular function and interfering with cellular fate, which can further develop into new methods of health care and disease intervention. In this review, we first introduce the working principle of TENGs and their working modes, and then summarize the current research status of cellular function regulation and fate determination stimulated by TENGs, and also analyze their application prospects for changing various processes of cell activity. Finally, we discuss the opportunities and challenges of TENGs in the fields of life science and biomedical engineering, and propose a variety of possibilities for their potential development direction.

Original languageEnglish
Article number20220090
JournalExploration
Volume3
Issue number4
DOIs
Publication statusPublished - Aug 2023

Keywords

  • bioelectricity
  • cellular fate determination
  • cellular function regulation
  • electrical stimulation
  • triboelectric nanogenerators

ASJC Scopus subject areas

  • General

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