Recent advances in green nanoparticulate systems for drug delivery: Efficient delivery and safety concern

Pik Ling Lam, Wai Yeung Wong, Zhaoxiang Bian, Chung Hin Chui, Roberto Gambari

Research output: Journal article publicationReview articleAcademic researchpeer-review

33 Citations (Scopus)

Abstract

Nanotechnology manipulates therapeutic agents at the nanoscale for the development of nanomedicines. However, there are current concerns over nanomedicines, mainly related to the possible toxicity of nanomaterials used for health medications. Due to their small size, they can enter the human body more readily than larger sized particles. Green chemistry encompasses the green synthesis of drug-loaded nanoparticles by reducing the use of hazardous materials in the synthesis process, thus reducing the adverse health impacts of pharmaceutics. This would greatly expand their potential in biomedical treatments. This review highlights the potential risks of nanomedicine formulations to health, delivery routes of green nanomedicines, recent advances in the development of green nanoscale systems for biomedical applications and future perspectives for the green development of nanomedicines.
Original languageEnglish
Pages (from-to)357-385
Number of pages29
JournalNanomedicine
Volume12
Issue number4
DOIs
Publication statusPublished - 1 Feb 2017

Keywords

  • drug delivery
  • green nanoparticles
  • nanomedicines
  • nanotoxicity
  • safety evaluation

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomedical Engineering
  • Materials Science(all)
  • Development

Cite this