Recent advances in developing new axially chiral phosphine ligands for asymmetric catalysis

Yue Ming Li, Fuk Yee Kwong, Wing Yiu Yu, Albert S.C. Chan

Research output: Journal article publicationReview articleAcademic researchpeer-review

118 Citations (Scopus)


This review article illustrates the concept and approach for designing new C2-symmetric chelating atropisomeric chiral phosphines containing heterocyclic scaffolds. The versatility in structural modification is highlighted, and that it offers an effective avenue to access chiral ligands of diverse electronic and steric properties for optimization in various catalytic asymmetric transformations. In this article, the uses of atropisomeric chiral phosphines in some asymmetric transformations such as hydrogenation and alkyl-/arylation reactions will be discussed with reference to updated literature findings as well as the author's original research.
Original languageEnglish
Pages (from-to)2119-2144
Number of pages26
JournalCoordination Chemistry Reviews
Issue number17-20
Publication statusPublished - 1 Sep 2007
Externally publishedYes


  • Asymmetric catalysis
  • Chiral ligands
  • Phosphines

ASJC Scopus subject areas

  • Chemistry(all)

Cite this