Real-time measurement of cellular refractive index and thickness using cell culture chip

J. J. Gu; Y. F. Yu; E. P. Li; S. H. Ng; P. H. Yap; X. Q. Zhou; T. H. Cheng; A. Q. Liu

Real-time measurement of cellular refractive index and thickness using cell culture chip

J. J. Gu
, Y. F. Yu
, E. P. Li
, S. H. Ng
, P. H. Yap
, X. Q. Zhou
, T. H. Cheng
, A. Q. Liu

Research output: Unpublished conference presentation (presented paper, abstract, poster) › Conference presentation (not published in journal/proceeding/book) › Academic research › peer-review

4 Citations (Scopus)

Abstract

This paper reports the measurement of refractive index (RI) and thickness of living cells using cell culture chip integrated with micro-indicators via immersion refractometry. In the experiment, the RI and the thickness of the cultured Madin-Darby canine kidney (MDCK) cell line are obtained simultaneously. As this method features high accuracy, no damage to a group of the living cells and real time measurement during long-term cell culture, it is promising for many applications such as detecting pathological changes of cells and cancer cell detection.

Original language	English
Pages	1873-1875
Number of pages	3
Publication status	Published - Oct 2008
Externally published	Yes
Event	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: 12 Oct 2008 → 16 Oct 2008

Conference

Conference	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
Country/Territory	United States
City	San Diego, CA
Period	12/10/08 → 16/10/08

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cell culture
Immersion refractometry
Lab-on-a-chip
Refractive index

ASJC Scopus subject areas

Chemical Engineering (miscellaneous)
Bioengineering

Cite this

@conference{1e269978af1b4b5791c4a09ce2dfa980,

title = "Real-time measurement of cellular refractive index and thickness using cell culture chip",

abstract = "This paper reports the measurement of refractive index (RI) and thickness of living cells using cell culture chip integrated with micro-indicators via immersion refractometry. In the experiment, the RI and the thickness of the cultured Madin-Darby canine kidney (MDCK) cell line are obtained simultaneously. As this method features high accuracy, no damage to a group of the living cells and real time measurement during long-term cell culture, it is promising for many applications such as detecting pathological changes of cells and cancer cell detection.",

keywords = "Cell culture, Immersion refractometry, Lab-on-a-chip, Refractive index",

author = "Gu, \{J. J.\} and Yu, \{Y. F.\} and Li, \{E. P.\} and Ng, \{S. H.\} and Yap, \{P. H.\} and Zhou, \{X. Q.\} and Cheng, \{T. H.\} and Liu, \{A. Q.\}",

year = "2008",

month = oct,

language = "English",

pages = "1873--1875",

note = "12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 ; Conference date: 12-10-2008 Through 16-10-2008",

}

Real-time measurement of cellular refractive index and thickness using cell culture chip. / Gu, J. J.; Yu, Y. F.; Li, E. P. et al.
2008. 1873-1875 Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.

Research output: Unpublished conference presentation (presented paper, abstract, poster) › Conference presentation (not published in journal/proceeding/book) › Academic research › peer-review

TY - CONF

T1 - Real-time measurement of cellular refractive index and thickness using cell culture chip

AU - Gu, J. J.

AU - Yu, Y. F.

AU - Li, E. P.

AU - Ng, S. H.

AU - Yap, P. H.

AU - Zhou, X. Q.

AU - Cheng, T. H.

AU - Liu, A. Q.

PY - 2008/10

Y1 - 2008/10

N2 - This paper reports the measurement of refractive index (RI) and thickness of living cells using cell culture chip integrated with micro-indicators via immersion refractometry. In the experiment, the RI and the thickness of the cultured Madin-Darby canine kidney (MDCK) cell line are obtained simultaneously. As this method features high accuracy, no damage to a group of the living cells and real time measurement during long-term cell culture, it is promising for many applications such as detecting pathological changes of cells and cancer cell detection.

AB - This paper reports the measurement of refractive index (RI) and thickness of living cells using cell culture chip integrated with micro-indicators via immersion refractometry. In the experiment, the RI and the thickness of the cultured Madin-Darby canine kidney (MDCK) cell line are obtained simultaneously. As this method features high accuracy, no damage to a group of the living cells and real time measurement during long-term cell culture, it is promising for many applications such as detecting pathological changes of cells and cancer cell detection.

KW - Cell culture

KW - Immersion refractometry

KW - Lab-on-a-chip

KW - Refractive index

UR - https://www.scopus.com/pages/publications/84902449565

M3 - Conference presentation (not published in journal/proceeding/book)

AN - SCOPUS:84902449565

SP - 1873

EP - 1875

T2 - 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008

Y2 - 12 October 2008 through 16 October 2008

ER -

Real-time measurement of cellular refractive index and thickness using cell culture chip

Abstract

Conference

UN SDGs

Keywords

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this