Reaction-Based Europium Complex for Specific Detection of Cysteine Over Homocysteine and Glutathione with Variable-Temperature Kinetic Studies

Yuk Wang Yip, Zhiyuan Yan, Ga Lai Law, Wing Tak Wong

    Research output: Journal article publicationJournal articleAcademic researchpeer-review

    1 Citation (Scopus)

    Abstract

    A water-soluble europium(III)-based probe, EuL, has been designed and synthesized for selective recognition of cysteine (Cys) over other structurally similar thiols and amino derivatives due to formation of a more stable and preferable seven-membered ring. Addition of Cys shows a significant response with quenching of over 90 % of the initial signal (Hcys: 10.5 %, GSH: 3.6 % respectively). A good linear correlation between the emission intensities and concentrations of Cys has been established.

    Original languageEnglish
    Pages (from-to)813-820
    Number of pages8
    JournalEuropean Journal of Inorganic Chemistry
    Volume2019
    Issue number6
    DOIs
    Publication statusPublished - 14 Feb 2019

    Keywords

    • Cysteine
    • Europium
    • Macrocycles
    • Reaction mechanisms
    • Sensors

    ASJC Scopus subject areas

    • Inorganic Chemistry

    Fingerprint

    Dive into the research topics of 'Reaction-Based Europium Complex for Specific Detection of Cysteine Over Homocysteine and Glutathione with Variable-Temperature Kinetic Studies'. Together they form a unique fingerprint.

    Cite this