Rational design of a GSH-responsive, water-soluble, heavy-atom-free anthracene-BODIPY photosensitizer for near-infrared fluorescence imaging guided photodynamic therapy

Keyphrases

• Anthracene 100%
• Rational Design 100%
• Water-soluble 100%
• Photosensitizer 100%
• Photodynamic Therapy 100%
• Boron Dipyrromethene (BODIPY) 100%
• Imaging-guided 100%
• Near-infrared Fluorescence Imaging 100%
• GSH-responsive 100%
• Heavy-atom-free 100%
• Heavy-atom-free Photosensitizers 66%
• Biocompatibility 33%
• Charge Transfer 33%
• In Cancer 33%
• Apoptosis 33%
• Cancer Cells 33%
• Triplet 33%
• Heavy Atoms 33%
• Fluorescence Imaging 33%
• Fluorescence Emission 33%
• Low Water Solubility 33%
• Emissive Property 33%
• Tumor-bearing Mice 33%
• High Fluorescence 33%
• Versatile Platform 33%
• Aqueous Solubility 33%
• Mouse in Vivo 33%
• Phototoxicity 33%
• Tumor Ablation 33%
• O2 Generation 33%
• GSH Level 33%
• Fluorescence Characteristics 33%
• Intracellular Glutathione 33%
• Spin-orbit 33%
• Major Challenges 33%
• Molecular Design Strategy 33%
• Reactive Oxygen Species Generation 33%
• Phototherapeutics 33%
• Piperazinium 33%
• Intersystem Crossing 33%
• Activatable Photosensitizer 33%
• Donor-acceptor Dyad 33%
• Photoinduced Charge Transfer 33%
• Selectivity Switch 33%

Chemistry

• Solubility 100%
• Water Soluble 100%
• Donor 100%
• Anthracene 100%
• Boron 100%
• Fluorescence Emission 50%
• Reactive Oxygen Metabolite 50%
• Intersystem Crossing [Singlet->triplet] 50%
• Molecular Design 50%
• Illumination 50%
• Glutathione 50%
• Hydrophile 50%
• Design Strategy 50%