Rapid reduction of pentavalent antimony by trypanothione: Potential relevance to antimonial activation

Siucheong Yan, Iris L.K. Wong, Ming Cheung Chow, Hongzhe Sun

Research output: Journal article publicationJournal articleAcademic researchpeer-review

21 Citations (Scopus)

Abstract

The dithiol trypanothione can reduce an antiparasitic pentavalent antimony agent to trivalent rapidly; this reduction process is both pH and temperature dependent and trypanothione may therefore play an important role in the activation of the drug.
Original languageEnglish
Pages (from-to)266-267
Number of pages2
JournalChemical Communications
Issue number2
DOIs
Publication statusPublished - 3 Feb 2003

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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