Rapid interrogation of the physical and chemical characteristics of salbutamol sulphate aerosol from a pressurised metered-dose inhaler (pMDI)

H. J. Tong; C. Fitzgerald; P. J. Gallimore; M. Kalberer; M. K. Kuimova; P. C. Seville; A. D. Ward; F. D. Pope

doi:10.1039/c4cc05803h

Rapid interrogation of the physical and chemical characteristics of salbutamol sulphate aerosol from a pressurised metered-dose inhaler (pMDI)

H. J. Tong
, C. Fitzgerald
, P. J. Gallimore
, M. Kalberer
, M. K. Kuimova
, P. C. Seville
, A. D. Ward
, F. D. Pope

Research output: Journal article publication › Journal article › Academic research › peer-review

19 Citations (Scopus)

Abstract

Individual micron-sized solid particles from a Salamol® pharmaceutical inhaler are stably captured in air using an optical trap for the first time. Raman spectroscopy of the levitated particles allows online interrogation of composition and deliquescent phase change within a high humidity environment that mimics the particle's travel from inhaler to lung. 2014

Original language	English
Pages (from-to)	15499-15502
Number of pages	4
Journal	Chemical Communications
Volume	50
Issue number	98
DOIs	https://doi.org/10.1039/c4cc05803h
Publication status	Published - 23 Nov 2014
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c4cc05803h

Cite this

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title = "Rapid interrogation of the physical and chemical characteristics of salbutamol sulphate aerosol from a pressurised metered-dose inhaler (pMDI)",

abstract = "Individual micron-sized solid particles from a Salamol{\textregistered} pharmaceutical inhaler are stably captured in air using an optical trap for the first time. Raman spectroscopy of the levitated particles allows online interrogation of composition and deliquescent phase change within a high humidity environment that mimics the particle's travel from inhaler to lung. 2014",

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Rapid interrogation of the physical and chemical characteristics of salbutamol sulphate aerosol from a pressurised metered-dose inhaler (pMDI). / Tong, H. J.; Fitzgerald, C.; Gallimore, P. J. et al.
In: Chemical Communications, Vol. 50, No. 98, 23.11.2014, p. 15499-15502.

Research output: Journal article publication › Journal article › Academic research › peer-review

TY - JOUR

T1 - Rapid interrogation of the physical and chemical characteristics of salbutamol sulphate aerosol from a pressurised metered-dose inhaler (pMDI)

AU - Tong, H. J.

AU - Fitzgerald, C.

AU - Gallimore, P. J.

AU - Kalberer, M.

AU - Kuimova, M. K.

AU - Seville, P. C.

AU - Ward, A. D.

AU - Pope, F. D.

PY - 2014/11/23

Y1 - 2014/11/23

N2 - Individual micron-sized solid particles from a Salamol® pharmaceutical inhaler are stably captured in air using an optical trap for the first time. Raman spectroscopy of the levitated particles allows online interrogation of composition and deliquescent phase change within a high humidity environment that mimics the particle's travel from inhaler to lung. 2014

AB - Individual micron-sized solid particles from a Salamol® pharmaceutical inhaler are stably captured in air using an optical trap for the first time. Raman spectroscopy of the levitated particles allows online interrogation of composition and deliquescent phase change within a high humidity environment that mimics the particle's travel from inhaler to lung. 2014

UR - https://www.scopus.com/pages/publications/84912083677

U2 - 10.1039/c4cc05803h

DO - 10.1039/c4cc05803h

M3 - Journal article

C2 - 25329335

AN - SCOPUS:84912083677

SN - 1359-7345

VL - 50

SP - 15499

EP - 15502

JO - Chemical Communications

JF - Chemical Communications

IS - 98

ER -

Rapid interrogation of the physical and chemical characteristics of salbutamol sulphate aerosol from a pressurised metered-dose inhaler (pMDI)

Abstract

ASJC Scopus subject areas

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