Rapid fabrication of complex 3D extracellular microenvironments by dynamic optical projection stereolithography

Aping Zhang, Xin Qu, Pranav Soman, Kolin C. Hribar, Jin W. Lee, Shaochen Chen, Sailing He

Research output: Journal article publicationJournal articleAcademic researchpeer-review

249 Citations (Scopus)


The topographic features of the extracelluar matrix (ECM) lay the foundation for cellular behavior. A novel biofabrication method using a digital-mirror device (DMD), called dynamic optical projection stereolithography (DOPsL) is demonstrated. This robust and versatile platform can generate complex biomimetic scaffolds within seconds. Such 3D scaffolds have promising potentials for studying cell interactions with microenvironments in vitro and in vivo. KGaA, Weinheim.
Original languageEnglish
Pages (from-to)4266-4270
Number of pages5
JournalAdvanced Materials
Issue number31
Publication statusPublished - 16 Aug 2012
Externally publishedYes


  • cell culture
  • extracelluar microenviroment
  • maskless lithography
  • optical projection stereolithography
  • soft material

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this