@article{6f7e3ae4ad7c44b186abbbf70ee9d894,
title = "Quinolizinium-based tunable pH fluorescent probes for imaging in live cells",
abstract = "A new class of quinolizinium-based tunable pH fluorescent probes for cell imaging was developed. The probes showed turn “On” fluorescence response upon acidification brought by a modulation of photoinduced electron transfer (PET) from the N,N-dialkyl aniline substituent to the quinolizinium core skeleton. These novel PET-based pH fluorescent probes displayed tunable emission properties in between 478 and 509 nm. Also, the probes exhibited tunable pH responsiveness with pKa ranging from <2.1 to 6.1 contributed by the steric effect of N,N-dialkyl anilines. They were successfully applied to in vivo pH sensing in lysosome in live cells.",
keywords = "Cellular imaging, pH probe, Photo-induced electron transfer, Quinolizinium",
author = "Sit, \{Hoi Yi\} and Deng, \{Jie Ren\} and Chan, \{Wing Cheung\} and Ko, \{Ben Chi Bun\} and Wong, \{Man Kin\}",
note = "Funding Information: We gratefully acknowledge the financial support from the Shenzhen Science and Technology Innovation Commission (JCYJ20170818104257975), Hong Kong Research Grants Council (PolyU 153001/17P), the State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University (G-ZVVG and G-UACN), and Innovation and Technology Commission (PRP/075/19FX). Funding Information: We gratefully acknowledge the financial support from the Shenzhen Science and Technology Innovation Commission ( JCYJ20170818104257975 ), Hong Kong Research Grants Council ( PolyU 153001/17P ), the State Key Laboratory of Chemical Biology and Drug Discovery , The Hong Kong Polytechnic University ( G-ZVVG and G-UACN ), and Innovation and Technology Commission ( PRP/075/19FX ). Publisher Copyright: {\textcopyright} 2022 Elsevier Ltd",
year = "2022",
month = sep,
doi = "10.1016/j.dyepig.2022.110541",
language = "English",
volume = "205",
journal = "Dyes and Pigments",
issn = "0143-7208",
publisher = "Elsevier B.V.",
}