Quinacrine and a novel apigenin dimer can synergistically increase the pentamidine susceptibility of the protozoan parasite Leishmania

Keyphrases

• Leishmania 100%
• Protozoan Parasites 100%
• Pentamidine 100%
• Apigenin 100%
• Quinacrine 100%
• Fractional Inhibitory Concentration Index 15%
• Synergistic Effect 10%
• Indexing Methods 10%
• Promastigote 10%
• Sensitizing Effect 10%
• Dose Effect 5%
• Verapamil 5%
• Drug-resistant Parasites 5%
• Vinblastine 5%
• Leishmania Donovani 5%
• Leishmania Enriettii 5%
• Mammalian Cells 5%
• Resistance Level 5%
• Non-associated 5%
• Leishmania Parasites 5%
• Sodium Stibogluconate 5%
• Quinidine 5%
• Quinine 5%
• ATP-binding Cassette Transporter A1 (ABCA1) 5%
• Resistant Cell Lines 5%
• Multi-target 5%
• Cancer Resistance 5%
• Proliferation Assay 5%
• ATP Binding Cassette Subfamily B Member 1 (ABCB1) 5%
• Amastigote 5%
• Accumulation Levels 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Apigenin 100%
• Protozoon 100%
• Leishmania 100%
• Dimer 100%
• Pentamidine 100%
• Mepacrine 100%
• Promastigote 10%
• ABC Transporter 5%
• Leishmania enriettii 5%
• High Performance Liquid Chromatography 5%
• Malignant Neoplasm 5%
• Verapamil 5%
• Vinblastine 5%
• Sodium Stibogluconate 5%
• Leishmania donovani 5%
• Drug Resistance 5%
• Quinidine 5%
• Amastigote 5%

Immunology and Microbiology

• Protozoa 100%
• Leishmania 100%
• Pentamidine 100%
• Wild Type 21%
• Fractional Inhibitory Concentration Index 15%
• Promastigote 10%
• Drug Resistance 5%
• High Performance Liquid Chromatography 5%
• Leishmania donovani 5%
• ABC Transporter 5%
• Leishmania enriettii 5%
• Sensitization 5%
• Sodium Stibogluconate 5%
• Resistant Cell Line 5%
• Amastigote 5%