Abstract
Cell chemotaxis is a phenomenon in which cells spatially sense the chemoattractant gradient in the extra-environment and move along this gradient. This paper illustrates the relationship between the chemoattractant gradient and the cell velocity quantitatively, using a single-cell motility assay method based on optically manipulated microsources. A case study was performed on leukemia cancer cells. Quantitative study indicates that the cell is sensitive to the gradient, and can move faster under a high gradient. Based on the quantitative relationship, a control strategy was proposed to realize automatically induced cell migration. The simulation results demonstrate the effectiveness and robustness of the proposed method.
Original language | English |
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Title of host publication | Proceedings of the IEEE Conference on Nanotechnology |
Publisher | IEEE |
Pages | 742-746 |
Number of pages | 5 |
ISBN (Electronic) | 9781479956227 |
DOIs | |
Publication status | Published - 26 Nov 2014 |
Externally published | Yes |
Event | 2014 14th IEEE International Conference on Nanotechnology, IEEE-NANO 2014 - Toronto, Canada Duration: 18 Aug 2014 → 21 Aug 2014 |
Conference
Conference | 2014 14th IEEE International Conference on Nanotechnology, IEEE-NANO 2014 |
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Country/Territory | Canada |
City | Toronto |
Period | 18/08/14 → 21/08/14 |
ASJC Scopus subject areas
- Electrical and Electronic Engineering
- Computer Science Applications
- Modelling and Simulation
- Instrumentation