Quantifying the effect of financial burden on health-related quality of life among patients with non-Hodgkin’s lymphomas

Richard Huan Xu, Eliza Lai Yi Wong, Yi Su, Hongyu Zhang, Wei Zhang, Dong Dong (Corresponding Author)

Research output: Journal article publicationJournal articleAcademic researchpeer-review

11 Citations (Scopus)


Objective: This study aimed to assess the association of health-related quality of life (HRQoL) with financial burden among patients with non-Hodgkin’s lymphoma (NHL) in China. Methods: The data used for the analyses came from a nationwide survey to investigate the health status of patients with lymphomas in China. The EQ-5D and EORTC QLQ-C30 were used to assess the patients’ HRQoL. The financial burden was calculated using both subjective and objective methods. The chi-squared test, Kruskal–Wallis one-way analysis of variance, ordinal least squared model, and Tobit regression model were used to estimate the relationship between financial burden and HRQoL. Results: Data from 1549 patients who reported living with 11 subtypes of NHL were elicited for our analysis. Approximately 60% of respondents reported suffering moderate to high financial burdens. A significant relationship between increased financial burden and reduced HRQoL scores, including the EQ-Index, physical, emotional, and social functioning, was identified. Compared with using an objective method to measure financial burden, patients with NHL indicated a poorer HRQoL when using a subjective method to measure financial burden. Conclusion: Medical professionals should select highly cost-effective treatments and ensure that patients understand the potential financial consequences of those treatments.

Original languageEnglish
Article number3325
Pages (from-to)1-15
Number of pages15
Issue number11
Publication statusPublished - 11 Nov 2020
Externally publishedYes


  • Cancer
  • Financial burden
  • Health-related quality of life
  • Non-Hodgkin’s lymphomas

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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