Pyridine-promoted diazotization of P[sbnd]H bonds with aryl diazonium tetrafluoroborates: Synthesis of azo organophosphorus compounds

Fan Cao, Lulu Si, Shipan Xu, Longzhi Zhu, Yu Liu, Weifeng Xu, Ke Wen Tang, Biquan Xiong, Wai Yeung Wong (Corresponding Author)

Research output: Journal article publicationJournal articleAcademic researchpeer-review

1 Citation (Scopus)

Abstract

A pyridine-promoted diazotization of P[sbnd]H bonds with aryl diazonium tetrafluoroborates is established. The reported method is simple and efficient for the synthesis of azo organophosphorus compounds with excellent yields, which avoids the adoption of complex and harsh reaction conditions and the addition of oxides, tolerating various kinds of functional groups. The synthesized azo organophosphorus compounds may have potential applications in organic chemistry and drug design.

Original languageEnglish
Article number154207
JournalTetrahedron Letters
Volume111
DOIs
Publication statusPublished - 23 Nov 2022

Keywords

  • Aryl diazonium tetrafluoroborates
  • Diazotization reaction
  • P[sbnd]H bonds
  • Transition-metal free synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Pyridine-promoted diazotization of P[sbnd]H bonds with aryl diazonium tetrafluoroborates: Synthesis of azo organophosphorus compounds'. Together they form a unique fingerprint.

Cite this