Abstract
Recent innovations in hyperpolarized Helium-3 magnetic resonance imaging (MRI) include the employment of MR tagging techniques for assessment of pulmonary deformation. Historically, such tagging methods have been successfully applied to cardiac research inspiring the development of computational techniques for the quantitative analysis of myocardial deformation. We present related research which concerns the calculation of kinematic quantities, such as displacement and strain, in the lung. Utilizing the high contrast tag lines as landmarks in the images and a recently developed fast n-D B-spline approximation algorithm, we fit a parametric object to the sparse tag line data to smoothly interpolate the underlying deformation field and, subsequently, extract lung kinematic information. We present results from a single human volunteer.
Original language | English |
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Title of host publication | 2007 4th IEEE International Symposium on Biomedical Imaging |
Subtitle of host publication | From Nano to Macro - Proceedings |
Pages | 368-371 |
Number of pages | 4 |
DOIs | |
Publication status | Published - 27 Nov 2007 |
Externally published | Yes |
Event | 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro; ISBI'07 - Arlington, VA, United States Duration: 12 Apr 2007 → 15 Apr 2007 |
Conference
Conference | 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro; ISBI'07 |
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Country/Territory | United States |
City | Arlington, VA |
Period | 12/04/07 → 15/04/07 |
Keywords
- B-splines
- Deformation analysis
- Hyperpolarized Helium-3
- Tagged MRI
ASJC Scopus subject areas
- Electrical and Electronic Engineering
- General Medicine