Pseudolaric acids: Isolation, bioactivity and synthetic studies

Pauline Chiu; Lai To Leung; Chi Bun Ko

doi:10.1039/b906520m

Pseudolaric acids: Isolation, bioactivity and synthetic studies

Pauline Chiu, Lai To Leung, Chi Bun Ko

Research output: Journal article publication › Review article › Academic research › peer-review

80 Citations (Scopus)

Abstract

The pseudolaric acids are diterpenoids isolated from the root bark of Pseudolarix amabilis, or the golden larch. Pseudolaric acids A and B are the major antifungal and anti-angiogenic congeners of this family of compounds. This review presents the results of the isolation, biological and synthetic studies of these natural products.

Original language	English
Pages (from-to)	1066-1083
Number of pages	18
Journal	Natural Product Reports
Volume	27
Issue number	7
DOIs	https://doi.org/10.1039/b906520m
Publication status	Published - 1 Jul 2010
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1039/b906520m

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title = "Pseudolaric acids: Isolation, bioactivity and synthetic studies",

abstract = "The pseudolaric acids are diterpenoids isolated from the root bark of Pseudolarix amabilis, or the golden larch. Pseudolaric acids A and B are the major antifungal and anti-angiogenic congeners of this family of compounds. This review presents the results of the isolation, biological and synthetic studies of these natural products.",

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AU - Chiu, Pauline

AU - Leung, Lai To

AU - Ko, Chi Bun

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N2 - The pseudolaric acids are diterpenoids isolated from the root bark of Pseudolarix amabilis, or the golden larch. Pseudolaric acids A and B are the major antifungal and anti-angiogenic congeners of this family of compounds. This review presents the results of the isolation, biological and synthetic studies of these natural products.

AB - The pseudolaric acids are diterpenoids isolated from the root bark of Pseudolarix amabilis, or the golden larch. Pseudolaric acids A and B are the major antifungal and anti-angiogenic congeners of this family of compounds. This review presents the results of the isolation, biological and synthetic studies of these natural products.

UR - https://www.scopus.com/pages/publications/77954676306

U2 - 10.1039/b906520m

DO - 10.1039/b906520m

M3 - Review article

C2 - 20405078

SN - 0265-0568

VL - 27

SP - 1066

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JO - Natural Product Reports

JF - Natural Product Reports

IS - 7

ER -

Pseudolaric acids: Isolation, bioactivity and synthetic studies

Abstract

ASJC Scopus subject areas

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