Proteomic Analysis of Secreted Vesicle Proteins from the Plant Cells

Research output: Chapter in book / Conference proceedingChapter in an edited book (as author)Academic researchpeer-review

Abstract

A working pipeline for proteomic analysis of secreted vesicle proteins from the plant cells has been developed using urea and mass spectrometry-compatible detergent RapiGest SF, where vesicles could be efficiently lysed and membrane-bound proteins could be efficiently dissolved and digested. The vesicle lysis and the protein digestion procedures are performed within one tube to minimize the protein loss. The protein digest is analyzed using LC-MS/MS after desalting with an SPE spin column.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages67-73
Number of pages7
Volume2841
DOIs
Publication statusPublished - 9 Aug 2024

Publication series

NameMethods in Molecular Biology
Volume2841
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • LC-MS/MS
  • Plant cells
  • Proteomic analysis
  • Vesicle proteins

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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