Prospective memory in non-psychotic first-degree relatives of patients with schizophrenia

Y. Wang, R.C.K. Chan, J. Cui, Y. Deng, J. Huang, H. Li, C. Yan, T. Xu, Z. Ma, X. Hong, Z. Li, H. Shi, Ho Keung David Shum

Research output: Journal article publicationJournal articleAcademic researchpeer-review

18 Citations (Scopus)

Abstract

Although a number of studies have found prospective memory (PM) impairment in patients with schizophrenia, very little is known about the PM performance in non-psychotic relatives of these patients. The current study aimed to explore the PM performance in non-psychotic first-degree relatives of these patients. Two groups of participants (26 non-psychotic first-degree relatives of schizophrenia patients and 26 healthy comparison participants) were administered three PM tasks (time-, event-, and activity-based) and a set of neurocognitive tests. Results showed that the relatives performed significantly worse than the comparisons on most indices of the PM tasks, with a similar pattern of impairment found in other neurocognitive measures. Together with findings from previous studies, results of the current study suggest that PM may be a potential endophenotype for schizophrenia. © 2009 Elsevier Ltd.
Original languageEnglish
Pages (from-to)285-290
Number of pages6
JournalPsychiatry Research
Volume179
Issue number3
DOIs
Publication statusPublished - 30 Oct 2010
Externally publishedYes

Keywords

  • First-degree relative
  • Non-psychotic
  • Prospective memory
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this