Abstract
Although a number of studies have found prospective memory (PM) impairment in patients with schizophrenia, very little is known about the PM performance in non-psychotic relatives of these patients. The current study aimed to explore the PM performance in non-psychotic first-degree relatives of these patients. Two groups of participants (26 non-psychotic first-degree relatives of schizophrenia patients and 26 healthy comparison participants) were administered three PM tasks (time-, event-, and activity-based) and a set of neurocognitive tests. Results showed that the relatives performed significantly worse than the comparisons on most indices of the PM tasks, with a similar pattern of impairment found in other neurocognitive measures. Together with findings from previous studies, results of the current study suggest that PM may be a potential endophenotype for schizophrenia. © 2009 Elsevier Ltd.
Original language | English |
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Pages (from-to) | 285-290 |
Number of pages | 6 |
Journal | Psychiatry Research |
Volume | 179 |
Issue number | 3 |
DOIs | |
Publication status | Published - 30 Oct 2010 |
Externally published | Yes |
Keywords
- First-degree relative
- Non-psychotic
- Prospective memory
- Schizophrenia
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry