TY - JOUR
T1 - Profiling of experiential pleasure, emotional regulation and emotion expression in patients with schizophrenia
AU - Zou, Y.-M.
AU - Ni, K.
AU - Yang, Z.-Y.
AU - Li, Y.
AU - Cai, X.-L.
AU - Xie, D.-J.
AU - Zhang, R.-T.
AU - Zhou, F.-C.
AU - Li, W.-X.
AU - Lui, S.S.Y.
AU - Shum, Ho Keung David
AU - Cheung, E.F.C.
AU - Chan, R.C.K.
PY - 2018/5/1
Y1 - 2018/5/1
N2 - Background: Emotion deficits may be the basis of negative symptoms in schizophrenia patients and they are prevalent in these patients. However, inconsistent findings about emotion deficits in schizophrenia suggest that there may be subtypes. Aim: The present study aimed to examine and profile experiential pleasure, emotional regulation and expression in patients with schizophrenia. Methods: A set of checklists specifically capturing experiential pleasure, emotional regulation, emotion expression, depressive symptoms and anhedonia were administered to 146 in-patients with schizophrenia and 73 demographically-matched healthy controls. Psychiatric symptoms and negative symptoms were also evaluated by a trained psychiatrist for patients with schizophrenia. Results: Two-stage cluster analysis and discriminant function analysis were used to analyze the profile of these measures in patients with schizophrenia. We found a three-cluster solution. Cluster 1 (n = 41) was characterized by a deficit in experiential pleasure and emotional regulation, Cluster 2 (n = 47) was characterized by a general deficit in experiential pleasure, emotional regulation and emotion expression, and Cluster 3 (n = 57) was characterized by a deficit in emotion expression. Results of a discriminant function analysis indicated that the three groups were reasonably discrete. Conclusion: The present findings suggest that schizophrenia patients can be classified into three subtypes based on experiential pleasure, emotional regulation and emotion expression, which are characterized by distinct clinical representations.
AB - Background: Emotion deficits may be the basis of negative symptoms in schizophrenia patients and they are prevalent in these patients. However, inconsistent findings about emotion deficits in schizophrenia suggest that there may be subtypes. Aim: The present study aimed to examine and profile experiential pleasure, emotional regulation and expression in patients with schizophrenia. Methods: A set of checklists specifically capturing experiential pleasure, emotional regulation, emotion expression, depressive symptoms and anhedonia were administered to 146 in-patients with schizophrenia and 73 demographically-matched healthy controls. Psychiatric symptoms and negative symptoms were also evaluated by a trained psychiatrist for patients with schizophrenia. Results: Two-stage cluster analysis and discriminant function analysis were used to analyze the profile of these measures in patients with schizophrenia. We found a three-cluster solution. Cluster 1 (n = 41) was characterized by a deficit in experiential pleasure and emotional regulation, Cluster 2 (n = 47) was characterized by a general deficit in experiential pleasure, emotional regulation and emotion expression, and Cluster 3 (n = 57) was characterized by a deficit in emotion expression. Results of a discriminant function analysis indicated that the three groups were reasonably discrete. Conclusion: The present findings suggest that schizophrenia patients can be classified into three subtypes based on experiential pleasure, emotional regulation and emotion expression, which are characterized by distinct clinical representations.
KW - Cluster analysis
KW - Experience
KW - Expression
KW - Regulation
KW - Schizophrenia
UR - http://www.scopus.com/inward/record.url?scp=85028431644&partnerID=8YFLogxK
U2 - 10.1016/j.schres.2017.08.048
DO - 10.1016/j.schres.2017.08.048
M3 - Journal article
SN - 0920-9964
VL - 195
SP - 396
EP - 401
JO - Schizophrenia Research
JF - Schizophrenia Research
ER -