Primo vascular system accompanying a blood vessel from tumor tissue and a method to distinguish it from the blood or the lymph system

Jaekwan Lim, Sungwoo Lee, Zhendong Su, Hong Bae Kim, Jung Sun Yoo, Kwang Sup Soh, Sungchul Kim, Yeon Hee Ryu

Research output: Journal article publicationJournal articleAcademic researchpeer-review

4 Citations (Scopus)


A primo vessel was observed in the abdominal cavity in the lung cancer mouse model, and its function as an extra metastatic path was observed. In this work, we found a primo vessel accompanying a blood vessel emanating from a tumor in the skin. We also presented simple and efficient criteria to distinguish a primo vessel from a blood or a lymph vessel and from a nerve. The criteria for using DAPI and Phalloidin will be useful in clinical situations to find and identify the primo vessels among the blood vessels, lymph vessels, or nerves in the tissue surrounding a tumor such as a melanoma or breast cancer.
Original languageEnglish
Article number949245
JournalEvidence-based Complementary and Alternative Medicine
Publication statusPublished - 12 Jun 2013
Externally publishedYes

ASJC Scopus subject areas

  • Complementary and alternative medicine

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