Practical synthetic approach to chiral sulfonimides (CSIs) - Chiral bronsted acids for organocatalysis

Hao He, Ling Yan Chen, Wai Yeung Wong, Wing Hong Chan, Albert W.M. Lee

Research output: Journal article publicationJournal articleAcademic researchpeer-review

42 Citations (Scopus)

Abstract

A general approach to the synthesis of optically pure 3,3'diaryl chiral sulfonimides (CSIs) from racemic BINOL has been developed. ortho-Lithiation is directed by the sulfonyl groups, and the resulting dihalides serve as the common precursors for the aryl-substituted CSIs. KGaA, Weinheim.
Original languageEnglish
Pages (from-to)4181-4184
Number of pages4
JournalEuropean Journal of Organic Chemistry
Issue number22
DOIs
Publication statusPublished - 1 Aug 2010
Externally publishedYes

Keywords

  • Bransted acids
  • Chirality
  • Organocatalysis
  • Sulfonimides

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry

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