Power to detect linkage based on multiple sets of data in the presence of locus heterogeneity: Comparative evaluation of model-based linkage methods for affected sib pair data

Keyphrases

• Evaluation Model 100%
• Locus Heterogeneity 100%
• Multiple Sets 100%
• Linkage Method 100%
• Affected Sib-pair 100%
• LOD Score 66%
• Adaptation 33%
• High Power 33%
• Rigorous Method 33%
• Complex Disorders 33%
• Genetic Screening 33%
• Posterior Probability 33%
• Overall Strength 33%
• Multiple Datasets 33%
• Model-free Methods 33%
• Intersample 33%
• Strength of Evidence 33%
• Score-based 33%
• Additional Power 33%
• Data Pooling 33%
• Genetic Linkage 33%
• Complicating Factors 33%

Mathematics

• Data Pair 100%
• Subsample 50%
• Complicating Factor 50%
• Pooled Data 50%
• Statistics 50%
• Probability Theory 50%
• High Power 50%