Poststroke depression in patients with small subcortical infarcts

Y. Chen; Xiangyan Chen; V.C.T. Mok; W.W.M. Lam; K.S. Wong; W.K. Tang

doi:10.1016/j.clineuro.2008.10.008

Poststroke depression in patients with small subcortical infarcts

Y. Chen, Xiangyan Chen, V.C.T. Mok, W.W.M. Lam, K.S. Wong, W.K. Tang

Research output: Journal article publication › Journal article › Academic research › peer-review

13 Citations (Scopus)

Abstract

Objectives: Small subcortical infarcts (SSIs) can result from small vessel disease (SVD) and intracranial and extracranial large artery disease (LAD). No study has explored poststroke depression (PSD) in different etiological types of SSIs. Methods: Patients with SSIs resulting from LAD and SVD were included in the study. Poststroke depression was evaluated with the 15-item version of the geriatric depression scale (GDS) 3 months after stroke. Results: Of the 127 patients with SSIs, 44 had LAD and 83 had SVD. The LAD group had a significantly higher mean GDS score and higher frequency of PSD (p < 0.05). The etiological type LAD was a significant independent risk factor for PSD. Conclusion: PSD is more common in patients with SSIs resulting from LAD. This suggests that cerebral blood perfusion may play an important role in the development of PSD. © 2008 Elsevier B.V. All rights reserved.

Original language	English
Pages (from-to)	256-260
Number of pages	5
Journal	Clinical Neurology and Neurosurgery
Volume	111
Issue number	3
DOIs	https://doi.org/10.1016/j.clineuro.2008.10.008
Publication status	Published - 1 Apr 2009
Externally published	Yes

Keywords

Carotid artery stenosis
Depression
Intracranial large artery disease
MRI
Small vessel disease
Stroke

ASJC Scopus subject areas

Surgery
Clinical Neurology

More information

10.1016/j.clineuro.2008.10.008

Cite this

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title = "Poststroke depression in patients with small subcortical infarcts",

abstract = "Objectives: Small subcortical infarcts (SSIs) can result from small vessel disease (SVD) and intracranial and extracranial large artery disease (LAD). No study has explored poststroke depression (PSD) in different etiological types of SSIs. Methods: Patients with SSIs resulting from LAD and SVD were included in the study. Poststroke depression was evaluated with the 15-item version of the geriatric depression scale (GDS) 3 months after stroke. Results: Of the 127 patients with SSIs, 44 had LAD and 83 had SVD. The LAD group had a significantly higher mean GDS score and higher frequency of PSD (p < 0.05). The etiological type LAD was a significant independent risk factor for PSD. Conclusion: PSD is more common in patients with SSIs resulting from LAD. This suggests that cerebral blood perfusion may play an important role in the development of PSD. {\textcopyright} 2008 Elsevier B.V. All rights reserved.",

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AU - Chen, Xiangyan

AU - Mok, V.C.T.

AU - Lam, W.W.M.

AU - Wong, K.S.

AU - Tang, W.K.

PY - 2009/4/1

Y1 - 2009/4/1

N2 - Objectives: Small subcortical infarcts (SSIs) can result from small vessel disease (SVD) and intracranial and extracranial large artery disease (LAD). No study has explored poststroke depression (PSD) in different etiological types of SSIs. Methods: Patients with SSIs resulting from LAD and SVD were included in the study. Poststroke depression was evaluated with the 15-item version of the geriatric depression scale (GDS) 3 months after stroke. Results: Of the 127 patients with SSIs, 44 had LAD and 83 had SVD. The LAD group had a significantly higher mean GDS score and higher frequency of PSD (p < 0.05). The etiological type LAD was a significant independent risk factor for PSD. Conclusion: PSD is more common in patients with SSIs resulting from LAD. This suggests that cerebral blood perfusion may play an important role in the development of PSD. © 2008 Elsevier B.V. All rights reserved.

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KW - Carotid artery stenosis

KW - Depression

KW - Intracranial large artery disease

KW - MRI

KW - Small vessel disease

KW - Stroke

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ER -

Poststroke depression in patients with small subcortical infarcts

Abstract

Keywords

ASJC Scopus subject areas

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