TY - JOUR
T1 - Poor Insight in Schizophrenia Patients in China
T2 - a Meta-Analysis of Observational Studies
AU - Li, Wen
AU - Zhang, Hong He
AU - Wang, Yu
AU - Zhang, Ling
AU - Ungvari, Gabor S.
AU - Cheung, Teris
AU - Xiang, Yu Tao
N1 - Funding Information:
The study was supported by the National Science and Technology Major Project for investigational new drug (2018ZX09201–014), the Beijing Municipal Science & Technology Commission (No. Z181100001518005), and the University of Macau (MYRG2019–00066-FHS).
Publisher Copyright:
© 2020, Springer Science+Business Media, LLC, part of Springer Nature.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/12/1
Y1 - 2020/12/1
N2 - Poor insight exists in all phases of schizophrenia and is associated with poor clinical prognosis and adverse psychosocial functioning. This is a meta-analysis examining the prevalence of poor insight and its correlates in Chinese patients with schizophrenia. Both major international (PubMed, EMBASE, PsycINFO, and Web of Science) and Chinese (WANFANG and CNKI) databases were systematically searched. The pooled prevalence of poor insight was calculated using the random-effects model. A total of 19 studies with 3112 schizophrenia patients were included. The prevalence of poor insight was 43.4% (95%CI: 36.0%–51.2%). Subgroup and meta-regression analyses revealed that the higher prevalence of poor insight was significantly associated with single-site design, smaller sample size, inpatient status, acute illness phase, higher male proportion, younger age, shorter duration of illness, lower study quality, and earlier publication year. Poor insight is common in Chinese schizophrenia patients. Considering the negative outcomes of poor insight, regular screening and effective psychosocial interventions should be delivered for this vulnerable population.
AB - Poor insight exists in all phases of schizophrenia and is associated with poor clinical prognosis and adverse psychosocial functioning. This is a meta-analysis examining the prevalence of poor insight and its correlates in Chinese patients with schizophrenia. Both major international (PubMed, EMBASE, PsycINFO, and Web of Science) and Chinese (WANFANG and CNKI) databases were systematically searched. The pooled prevalence of poor insight was calculated using the random-effects model. A total of 19 studies with 3112 schizophrenia patients were included. The prevalence of poor insight was 43.4% (95%CI: 36.0%–51.2%). Subgroup and meta-regression analyses revealed that the higher prevalence of poor insight was significantly associated with single-site design, smaller sample size, inpatient status, acute illness phase, higher male proportion, younger age, shorter duration of illness, lower study quality, and earlier publication year. Poor insight is common in Chinese schizophrenia patients. Considering the negative outcomes of poor insight, regular screening and effective psychosocial interventions should be delivered for this vulnerable population.
KW - Meta-analysis
KW - Poor insight
KW - Prevalence
KW - Schizophrenia
UR - http://www.scopus.com/inward/record.url?scp=85086461385&partnerID=8YFLogxK
U2 - 10.1007/s11126-020-09786-7
DO - 10.1007/s11126-020-09786-7
M3 - Review article
C2 - 32529379
AN - SCOPUS:85086461385
SN - 0033-2720
VL - 91
SP - 1017
EP - 1031
JO - Psychiatric Quarterly
JF - Psychiatric Quarterly
IS - 4
ER -
