Polymer nanofiber composites

Natural extracellular matrix (ECM) provides a model for designing and developing synthetic tissue scaffolds intended for tissue repair and regeneration. Among all processing techniques, electrospinning has received considerable amount of interest due to its simple and versatile approach to produce nonwoven membranes that resemble the ECM. The ability to produce micro/nano materials with various compositions, fiber sizes and fiber arrangements make electrospinning a versatile technique for fabricating biomimetic structures for tissue engineering applications. These features ensure that the biological, chemical, and mechanical properties of the scaffolds can be controlled. Through this review, we illustrate some common electrospinning techniques used for producing composite fibers and highlight their use for tissue scaffold applications.