PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial load

Keyphrases

• Escherichia Coli 100%
• Bacterial Load 100%
• Neuroimmune Response 100%
• Sickness Behavior 100%
• Protein Kinase R 100%
• Sickness 50%
• Corticotropin-releasing Factor 40%
• Quantitative PCR 30%
• Systemic Inflammation 30%
• Neuroimmune Signaling 30%
• Tumor Necrosis Factor-α 20%
• Motor Impairment 20%
• Wild Mice 20%
• Behavioural Component 20%
• Hypothalamus 20%
• Anorexia 20%
• Social Withdrawal 20%
• Burrow 20%
• Hormone Response 20%
• Corticosterone Response 20%
• Social Interaction 10%
• Hippocampus 10%
• Liver 10%
• Inducible Nitric Oxide Synthase 10%
• Interleukin-1β 10%
• Escherichia Coli Infections 10%
• Open Field Activity 10%
• Interleukin-6 10%
• Test Performance 10%
• Inflammatory Response 10%
• Serine-threonine Kinase 10%
• Host Defense 10%
• Object of Activity 10%
• Neutrophil Count 10%
• Cyclooxygenase-2 10%
• Fluid Injection 10%
• Corticosterone 10%
• Fever 10%
• Exploratory Activity 10%
• Dysregulation 10%
• Plasma Corticosterone 10%
• Dysregulated 10%
• Food Consumption 10%
• Injection Site 10%
• Inflammatory Gene Expression 10%
• Hormone Expression 10%
• Lavage Fluid 10%
• Bacterial 16S 10%
• Bacterial Titer 10%
• Plate Count 10%
• Blood Fluid 10%
• 16S Ribosomal DNA 10%
• Rotarod Test 10%
• Blood Smear 10%
• Age of Infection 10%

Immunology and Microbiology

• Escherichia coli 100%
• Bacterial Load 100%
• Corticotropin-Releasing Hormone 80%
• Systemic Inflammation 60%
• Real Time Polymerase Chain Reaction 60%
• Tumor Necrosis Factor 40%
• Hypothalamus 40%
• Wild Type Mouse 40%
• Hormone Response 40%
• Blood Plasma 20%
• Interleukin-1 20%
• Inflammation Response 20%
• Hippocampus 20%
• Host Resistance 20%
• Gene Expression 20%
• ELISA 20%
• Titer 20%
• Interleukin 6 20%
• Rotarod Test 20%
• Corticosterone Blood Level 20%
• Lavage Fluid 20%
• Wild Type 20%
• Neutrophil 20%
• Plate Count 20%
• Serine 20%
• Threonine 20%
• Cyclooxygenase 20%

Neuroscience

• Protein Kinase R 100%
• Sickness Behavior 100%
• Corticosterone 40%
• Corticotropin-Releasing Hormone 40%
• Real-Time Polymerase Chain Reaction 30%
• Anorexia 20%
• Hypothalamus 20%
• Stereotypic Movement Disorder 20%
• Blood Plasma 20%
• Interleukin 6 10%
• ELISA 10%
• Hippocampus 10%
• Social Interaction 10%
• Gene Expression 10%
• Protein Serine Threonine Kinase 10%
• Cyclooxygenase 2 10%
• DNA 16S 10%