TY - JOUR
T1 - Physical activity is higher in patients with left ventricular assist device compared with chronic heart failure
AU - Moreno-Suarez, Ignacio
AU - Liew, Sylvia
AU - Dembo, Lawrence G.
AU - Larbalestier, Robert
AU - Maiorana, Andrew
N1 - Funding Information:
This project was supported by a Heart Foundation of Australia Vanguard Grant (101040). I. M.-S. was supported by a PhD Scholarship funded by the Heart and Lung Transplant Foundation of Western Australia and Curtin University. Authors would like to thank the patients for taking part in the study. We also thank the Advanced Heart Failure and Cardiac Transplant Service team of Royal Perth/Fiona Stanley Hospitals for their support of the study.
Publisher Copyright:
© Lippincott Williams & Wilkins.
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Purpose Left ventricular assist devices (LVAD) are associated with an increased aerobic capacity in patients with chronic heart failure (CHF). However, studies evaluating the impact of LVAD implantation on physical activity (PA) are lacking. The aim of this study was to compare daily PA levels in participants with LVAD with well-matched CHF participants. Methods Sixteen participants with an LVAD (age, 59.1 ± 10.8 yr) were case-matched to 16 participants with advanced CHF (age, 58.3 ± 8.7 yr), who were listed or being considered for cardiac transplantation. Participants underwent a cardiopulmonary exercise test to determine peak oxygen consumption (V-O2 peak). Physical activity was monitored continuously for seven consecutive days with an Actiheart monitor. Results V-O2 peak in the CHF group (12.3 ± 3.5 mL·kg-1·min-1) was not significantly different to the LVAD group before LVAD implantation (10.4 ± 2.1 mL·kg-1·min-1), but was lower than in the LVAD group after implantation (15.8 ± 4.3 mL·kg-1·min-1; P < 0.05). Physical activity was higher in the LVAD (19.7 ± 6.4 kJ·kg-1·d-1) compared with the CHF group (11.6 ± 6.9 kJ·kg-1·d-1; P = 0.001). The LVAD participants spent more time performing moderate-intensity PA than their CHF counterparts (median, 26 min·d-1; interquartile range, 24-40 min·d-1 vs median, 12 min·d-1; interquartile range, 9-16 min·d-1; P < 0.001). Physical activity was correlated with V-O2 peak (r = 0.582; P = 0.001) across participants in the CHF and LVAD groups. Conclusions Higher levels of PA were observed in participants with LVAD compared with patients with advanced CHF. This may be due to a higher V-O2 peak, resulting in an improved capacity to perform activities of daily living with less symptoms.
AB - Purpose Left ventricular assist devices (LVAD) are associated with an increased aerobic capacity in patients with chronic heart failure (CHF). However, studies evaluating the impact of LVAD implantation on physical activity (PA) are lacking. The aim of this study was to compare daily PA levels in participants with LVAD with well-matched CHF participants. Methods Sixteen participants with an LVAD (age, 59.1 ± 10.8 yr) were case-matched to 16 participants with advanced CHF (age, 58.3 ± 8.7 yr), who were listed or being considered for cardiac transplantation. Participants underwent a cardiopulmonary exercise test to determine peak oxygen consumption (V-O2 peak). Physical activity was monitored continuously for seven consecutive days with an Actiheart monitor. Results V-O2 peak in the CHF group (12.3 ± 3.5 mL·kg-1·min-1) was not significantly different to the LVAD group before LVAD implantation (10.4 ± 2.1 mL·kg-1·min-1), but was lower than in the LVAD group after implantation (15.8 ± 4.3 mL·kg-1·min-1; P < 0.05). Physical activity was higher in the LVAD (19.7 ± 6.4 kJ·kg-1·d-1) compared with the CHF group (11.6 ± 6.9 kJ·kg-1·d-1; P = 0.001). The LVAD participants spent more time performing moderate-intensity PA than their CHF counterparts (median, 26 min·d-1; interquartile range, 24-40 min·d-1 vs median, 12 min·d-1; interquartile range, 9-16 min·d-1; P < 0.001). Physical activity was correlated with V-O2 peak (r = 0.582; P = 0.001) across participants in the CHF and LVAD groups. Conclusions Higher levels of PA were observed in participants with LVAD compared with patients with advanced CHF. This may be due to a higher V-O2 peak, resulting in an improved capacity to perform activities of daily living with less symptoms.
KW - CHRONIC HEART FAILURE
KW - LEFT VENTRICULAR ASSIST DEVICE
KW - PEAK OXYGEN CONSUMPTION
KW - PHYSICAL ACTIVITY
KW - QUALITY OF LIFE
UR - http://www.scopus.com/inward/record.url?scp=85076468460&partnerID=8YFLogxK
U2 - 10.1249/MSS.0000000000002104
DO - 10.1249/MSS.0000000000002104
M3 - Journal article
C2 - 31834251
AN - SCOPUS:85076468460
SN - 0195-9131
VL - 52
SP - 1
EP - 7
JO - Medicine and Science in Sports and Exercise
JF - Medicine and Science in Sports and Exercise
IS - 1
ER -