Particle deposition in a CT-scanned human lung airway

H. Y. Luo, Yang Liu

Research output: Journal article publicationJournal articleAcademic researchpeer-review

36 Citations (Scopus)

Abstract

The particle deposition in a computerized tomography (CT)-scanned human lung was numerically investigated. The five-generation airway is extracted from the trachea to segmental bronchi of a 60-year-old Chinese male patient. Computations were carried out in the flow rate range of 210-630 ml/s (Reynolds number range of 1000-3000) and particle size of 2-10 μm (Stokes number range of 0.0007-0.049). To count the effect of laryngeal jet on trachea inlet, the trachea was extended and modified to simulate the larynx, consequently the inlet velocity profile is biased towards the rear wall. The laryngeal jet-induced turbulence was simulated using low Reynolds number (LRN) κ-ω turbulent model. Particle deposition patterns, deposition efficiency and deposition factor were studied in detail. The turbulent flow has significant effect on the particle deposition, and the present deposition factor is compared well with the available data.
Original languageEnglish
Pages (from-to)1869-1876
Number of pages8
JournalJournal of Biomechanics
Volume42
Issue number12
DOIs
Publication statusPublished - 25 Aug 2009

Keywords

  • Human lung model
  • Numerical simulation
  • Particle deposition
  • Turbulent flow

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine
  • Biomedical Engineering
  • Rehabilitation

Cite this