Palladium(II)-catalyzed othro-C-H-benzoxylation of 2-arylpyridines by oxidative coupling with aryl acylperoxides

Wing Nga Sit; Chun Wo Chan; Wing Yiu Yu

doi:10.3390/molecules18044403

Palladium(II)-catalyzed othro-C-H-benzoxylation of 2-arylpyridines by oxidative coupling with aryl acylperoxides

Wing Nga Sit
, Chun Wo Chan
, Wing Yiu Yu

The Hong Kong Polytechnic University

Research output: Journal article publication › Journal article › Academic research › peer-review

23 Citations (Scopus)

Abstract

A palladium(II)-catalyzed ortho-benzoxylation of 2-arylpyridines with aryl acylperoxides was developed. With pyridyl as directing group, the benzoxylation reaction exhibits remarkable regioselectivity and excellent functional group tolerance, providing the products in up to 87% yield.

Original language	English
Pages (from-to)	4403-4418
Number of pages	16
Journal	Molecules
Volume	18
Issue number	4
DOIs	https://doi.org/10.3390/molecules18044403
Publication status	Published - 1 Apr 2013

Keywords

C-H bond
Oxidation
Palladium

ASJC Scopus subject areas

General Medicine
Organic Chemistry

More information

10.3390/molecules18044403

http://hdl.handle.net/10397/16859

Cite this

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title = "Palladium(II)-catalyzed othro-C-H-benzoxylation of 2-arylpyridines by oxidative coupling with aryl acylperoxides",

abstract = "A palladium(II)-catalyzed ortho-benzoxylation of 2-arylpyridines with aryl acylperoxides was developed. With pyridyl as directing group, the benzoxylation reaction exhibits remarkable regioselectivity and excellent functional group tolerance, providing the products in up to 87\% yield.",

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AU - Sit, Wing Nga

AU - Chan, Chun Wo

AU - Yu, Wing Yiu

PY - 2013/4/1

Y1 - 2013/4/1

N2 - A palladium(II)-catalyzed ortho-benzoxylation of 2-arylpyridines with aryl acylperoxides was developed. With pyridyl as directing group, the benzoxylation reaction exhibits remarkable regioselectivity and excellent functional group tolerance, providing the products in up to 87% yield.

AB - A palladium(II)-catalyzed ortho-benzoxylation of 2-arylpyridines with aryl acylperoxides was developed. With pyridyl as directing group, the benzoxylation reaction exhibits remarkable regioselectivity and excellent functional group tolerance, providing the products in up to 87% yield.

KW - C-H bond

KW - Oxidation

KW - Palladium

UR - https://www.scopus.com/pages/publications/84876762858

U2 - 10.3390/molecules18044403

DO - 10.3390/molecules18044403

M3 - Journal article

C2 - 23591922

SN - 1420-3049

VL - 18

SP - 4403

EP - 4418

JO - Molecules

JF - Molecules

IS - 4

ER -

Palladium(II)-catalyzed othro-C-H-benzoxylation of 2-arylpyridines by oxidative coupling with aryl acylperoxides

Abstract

Keywords

ASJC Scopus subject areas

More information

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