Palladium(II)-catalyzed othro-C-H-benzoxylation of 2-arylpyridines by oxidative coupling with aryl acylperoxides

Wing Nga Sit, Chun Wo Chan, Wing Yiu Yu

Research output: Journal article publicationJournal articleAcademic researchpeer-review

19 Citations (Scopus)

Abstract

A palladium(II)-catalyzed ortho-benzoxylation of 2-arylpyridines with aryl acylperoxides was developed. With pyridyl as directing group, the benzoxylation reaction exhibits remarkable regioselectivity and excellent functional group tolerance, providing the products in up to 87% yield.
Original languageEnglish
Pages (from-to)4403-4418
Number of pages16
JournalMolecules
Volume18
Issue number4
DOIs
Publication statusPublished - 1 Apr 2013

Keywords

  • C-H bond
  • Oxidation
  • Palladium

ASJC Scopus subject areas

  • Medicine(all)
  • Organic Chemistry

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