Palladium-Phenylpyrazolylphosphine-Catalyzed Cross-Coupling of Alkenyl Pivalates

Zicong Chen, Chau Ming So (Corresponding Author)

Research output: Journal article publicationJournal articleAcademic researchpeer-review

Abstract

Palladium-catalyzed cross-coupling reactions are indispensable tools for C−C bond formation, and new catalyst development remains a powerful driving force in this field. In this study, a new type of easily accessible phenylpyrazole phosphine ligand is developed. The catalyst generated from Pd(OAc)2 and PP-Phos (L15) is highly effective in the palladium-catalyzed cross-coupling of alkenyl pivalates with organomagnesium reagents. The reaction accommodates a broad scope of alkenyl carboxylates under mild conditions, providing an alternative but practical way to the synthesis of multi-substituted alkenes in value.

Original languageEnglish
Pages (from-to)776-779
Number of pages4
JournalAsian Journal of Organic Chemistry
Volume10
Issue number4
DOIs
Publication statusPublished - Apr 2021

Keywords

  • alkene
  • alkenyl pivalate
  • cross-coupling
  • heterocyclic phosphine
  • palladium-catalyzed

ASJC Scopus subject areas

  • Organic Chemistry

Cite this