Palladium-catalyzed oxidative cross-coupling reaction of arylboronic acids with diazoesters for stereoselective synthesis of (E)-α,β- diarylacrylates

Yuk Tai Tsoi, Zhongyuan Zhou, Albert S.C. Chan, Wing Yiu Yu

Research output: Journal article publicationJournal articleAcademic researchpeer-review

60 Citations (Scopus)

Abstract

A Pd-catalyzed oxidative cross-coupling reaction of arylboronic acids with α-diazoesters was achieved using molecular oxygen as the sole reoxidant, and E-α,β-diarylacrylates were obtained in good yields and >20:1 E-to-Z selectivity.
Original languageEnglish
Pages (from-to)4506-4509
Number of pages4
JournalOrganic Letters
Volume12
Issue number20
DOIs
Publication statusPublished - 15 Oct 2010

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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