Palladium-catalyzed cross coupling reaction of benzyl bromides with diazoesters for stereoselective synthesis of (E)-α,β-diarylacrylates

Wing Yiu Yu; Yuk Tai Tsoi; Zhongyuan Zhou; Albert S.C. Chan

doi:10.1021/ol8026076

Palladium-catalyzed cross coupling reaction of benzyl bromides with diazoesters for stereoselective synthesis of (E)-α,β-diarylacrylates

Wing Yiu Yu, Yuk Tai Tsoi, Zhongyuan Zhou, Albert S.C. Chan

Research output: Journal article publication › Journal article › Academic research › peer-review

91 Citations (Scopus)

Abstract

(Chemical Equation Presented) A Pd-catalyzed cross-coupling reaction of benzyl bromides with α-aryldiazoesters is described, and E-α,β-diarylacrylates were obtained in good yields and excellent E-to-Z selectivity (>20:1).

Original language	English
Pages (from-to)	469-472
Number of pages	4
Journal	Organic Letters
Volume	11
Issue number	2
DOIs	https://doi.org/10.1021/ol8026076
Publication status	Published - 15 Jan 2009

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol8026076

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title = "Palladium-catalyzed cross coupling reaction of benzyl bromides with diazoesters for stereoselective synthesis of (E)-α,β-diarylacrylates",

abstract = "(Chemical Equation Presented) A Pd-catalyzed cross-coupling reaction of benzyl bromides with α-aryldiazoesters is described, and E-α,β-diarylacrylates were obtained in good yields and excellent E-to-Z selectivity (>20:1).",

author = "Yu, {Wing Yiu} and Tsoi, {Yuk Tai} and Zhongyuan Zhou and Chan, {Albert S.C.}",

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journal = "Organic Letters",

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T1 - Palladium-catalyzed cross coupling reaction of benzyl bromides with diazoesters for stereoselective synthesis of (E)-α,β-diarylacrylates

AU - Yu, Wing Yiu

AU - Tsoi, Yuk Tai

AU - Zhou, Zhongyuan

AU - Chan, Albert S.C.

PY - 2009/1/15

Y1 - 2009/1/15

N2 - (Chemical Equation Presented) A Pd-catalyzed cross-coupling reaction of benzyl bromides with α-aryldiazoesters is described, and E-α,β-diarylacrylates were obtained in good yields and excellent E-to-Z selectivity (>20:1).

AB - (Chemical Equation Presented) A Pd-catalyzed cross-coupling reaction of benzyl bromides with α-aryldiazoesters is described, and E-α,β-diarylacrylates were obtained in good yields and excellent E-to-Z selectivity (>20:1).

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U2 - 10.1021/ol8026076

DO - 10.1021/ol8026076

M3 - Journal article

C2 - 19099492

SN - 1523-7060

VL - 11

SP - 469

EP - 472

JO - Organic Letters

JF - Organic Letters

IS - 2

ER -

Palladium-catalyzed cross coupling reaction of benzyl bromides with diazoesters for stereoselective synthesis of (E)-α,β-diarylacrylates

Abstract

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