Palladium-catalyzed cross coupling reaction of benzyl bromides with diazoesters for stereoselective synthesis of (E)-α,β-diarylacrylates

Wing Yiu Yu, Yuk Tai Tsoi, Zhongyuan Zhou, Albert S.C. Chan

Research output: Journal article publicationJournal articleAcademic researchpeer-review

81 Citations (Scopus)

Abstract

(Chemical Equation Presented) A Pd-catalyzed cross-coupling reaction of benzyl bromides with α-aryldiazoesters is described, and E-α,β-diarylacrylates were obtained in good yields and excellent E-to-Z selectivity (>20:1).
Original languageEnglish
Pages (from-to)469-472
Number of pages4
JournalOrganic Letters
Volume11
Issue number2
DOIs
Publication statusPublished - 15 Jan 2009

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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