Palladium-catalyzed cross-coupling of aryl halides using organotitanium nucleophiles

Hang Wai Lee; Fuk Loi Lam; Chau Ming So; Chak Po Lau; Albert S.C. Chan; Fuk Yee Kwong

doi:10.1002/anie.200904033

Palladium-catalyzed cross-coupling of aryl halides using organotitanium nucleophiles

Hang Wai Lee
, Fuk Loi Lam
, Chau Ming So
, Chak Po Lau
, Albert S.C. Chan
, Fuk Yee Kwong

Research output: Journal article publication › Journal article › Academic research › peer-review

78 Citations (Scopus)

Abstract

They make a good couple: Catalysts generated from Pd (OAc)2and indolylphosphine ligands are highly effective in the titanium-mediated coupling of aryl halides. Catalyst loadings as low as 0.05 mol % Pd can be used. The mild reaction conditions also allow the coupling of aryl sulfonyl chlorides with aryl titanium reagents to generate diaryl sulfones. KGaA.

Original language	English
Pages (from-to)	7436-7439
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	48
Issue number	40
DOIs	https://doi.org/10.1002/anie.200904033
Publication status	Published - 21 Sept 2009

Keywords

Cross-coupling
Palladium
Phosphanes
Sulfones
Titanium

ASJC Scopus subject areas

Catalysis
General Chemistry

More information

10.1002/anie.200904033

Cite this

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abstract = "They make a good couple: Catalysts generated from Pd (OAc)2and indolylphosphine ligands are highly effective in the titanium-mediated coupling of aryl halides. Catalyst loadings as low as 0.05 mol \% Pd can be used. The mild reaction conditions also allow the coupling of aryl sulfonyl chlorides with aryl titanium reagents to generate diaryl sulfones. KGaA.",

keywords = "Cross-coupling, Palladium, Phosphanes, Sulfones, Titanium",

author = "Lee, \{Hang Wai\} and Lam, \{Fuk Loi\} and So, \{Chau Ming\} and Lau, \{Chak Po\} and Chan, \{Albert S.C.\} and Kwong, \{Fuk Yee\}",

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AU - Lam, Fuk Loi

AU - So, Chau Ming

AU - Lau, Chak Po

AU - Chan, Albert S.C.

AU - Kwong, Fuk Yee

PY - 2009/9/21

Y1 - 2009/9/21

N2 - They make a good couple: Catalysts generated from Pd (OAc)2and indolylphosphine ligands are highly effective in the titanium-mediated coupling of aryl halides. Catalyst loadings as low as 0.05 mol % Pd can be used. The mild reaction conditions also allow the coupling of aryl sulfonyl chlorides with aryl titanium reagents to generate diaryl sulfones. KGaA.

AB - They make a good couple: Catalysts generated from Pd (OAc)2and indolylphosphine ligands are highly effective in the titanium-mediated coupling of aryl halides. Catalyst loadings as low as 0.05 mol % Pd can be used. The mild reaction conditions also allow the coupling of aryl sulfonyl chlorides with aryl titanium reagents to generate diaryl sulfones. KGaA.

KW - Cross-coupling

KW - Palladium

KW - Phosphanes

KW - Sulfones

KW - Titanium

UR - https://www.scopus.com/pages/publications/70349911457

U2 - 10.1002/anie.200904033

DO - 10.1002/anie.200904033

M3 - Journal article

C2 - 19731296

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 40

ER -

Palladium-catalyzed cross-coupling of aryl halides using organotitanium nucleophiles

Abstract

Keywords

ASJC Scopus subject areas

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