Palladium-catalyzed cross-coupling of aryl halides using organotitanium nucleophiles

Hang Wai Lee, Fuk Loi Lam, Chau Ming So, Chak Po Lau, Albert S.C. Chan, Fuk Yee Kwong

Research output: Journal article publicationJournal articleAcademic researchpeer-review

55 Citations (Scopus)


They make a good couple: Catalysts generated from Pd (OAc)2and indolylphosphine ligands are highly effective in the titanium-mediated coupling of aryl halides. Catalyst loadings as low as 0.05 mol % Pd can be used. The mild reaction conditions also allow the coupling of aryl sulfonyl chlorides with aryl titanium reagents to generate diaryl sulfones. KGaA.
Original languageEnglish
Pages (from-to)7436-7439
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number40
Publication statusPublished - 21 Sep 2009


  • Cross-coupling
  • Palladium
  • Phosphanes
  • Sulfones
  • Titanium

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Cite this