Palladium-catalyzed cross-coupling of aryl halides using organotitanium nucleophiles

Hang Wai Lee, Fuk Loi Lam, Chau Ming So, Chak Po Lau, Albert S.C. Chan, Fuk Yee Kwong

Research output: Journal article publicationJournal articleAcademic researchpeer-review

50 Citations (Scopus)

Abstract

They make a good couple: Catalysts generated from Pd (OAc)2and indolylphosphine ligands are highly effective in the titanium-mediated coupling of aryl halides. Catalyst loadings as low as 0.05 mol % Pd can be used. The mild reaction conditions also allow the coupling of aryl sulfonyl chlorides with aryl titanium reagents to generate diaryl sulfones. KGaA.
Original languageEnglish
Pages (from-to)7436-7439
Number of pages4
JournalAngewandte Chemie - International Edition
Volume48
Issue number40
DOIs
Publication statusPublished - 21 Sep 2009

Keywords

  • Cross-coupling
  • Palladium
  • Phosphanes
  • Sulfones
  • Titanium

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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