@article{2844328fca994165bda75a147b27ac16,
title = "Palladium-Catalyzed Chemoselective Borylation of (Poly)halogenated Aryl Triflates and Their Application in Consecutive Reactions",
abstract = "This study reports the palladium-catalyzed chemoselective borylation of (poly)halogenated aryl triflates with a reactivity order of C−Cl>C−OTf. A catalyst system comprising Pd(OAc)2 and SelectPhos (L1) enables a reaction with high reactivity and chemoselectivity. The consecutively chemoselective borylation reaction followed by the chemoselective intermolecular Suzuki-Miyaura reaction can be performed using a one-pot two-step approach to synthesize unsymmetrical biaryl compounds containing the triflate moiety. The reaction can be scaled up to the gram scale without diminishing the yield and chemoselectivity. (Figure presented.).",
keywords = "(Poly)halogenated aryl triflates, Borylation, Chemoselective reaction, Palladium, Phosphines",
author = "Ng, {Shan Shan} and Zicong Chen and Yuen, {On Ying} and So, {Chau Ming}",
note = "Funding Information: We thank the National Natural Science Foundation of China (21972122) and the Research Grants Council of the Hong Kong Special Administrative Region, China (PolyU 15302821, 15300220, and 25301819) for financial support. We are grateful to Dr. Pui-kin So (PolyU) for the assistance in HRMS analysis, and Dr. Siu-cheong Yan, Kenneth (PolyU) for the assistance in NMR analysis. Funding Information: We thank the National Natural Science Foundation of China (21972122) and the Research Grants Council of the Hong Kong Special Administrative Region, China (PolyU 15302821, 15300220, and 25301819) for financial support. We are grateful to Dr. Pui‐kin So (PolyU) for the assistance in HRMS analysis, and Dr. Siu‐cheong Yan, Kenneth (PolyU) for the assistance in NMR analysis. Publisher Copyright: {\textcopyright} 2022 Wiley-VCH GmbH.",
year = "2022",
month = apr,
day = "26",
doi = "10.1002/adsc.202101501",
language = "English",
volume = "364",
pages = "1596--1601",
journal = "Advanced Synthesis and Catalysis",
issn = "1615-4150",
publisher = "Wiley-VCH Verlag",
number = "9",
}