Palladium-catalyzed borylation of aryl mesylates and tosylates and their applications in one-pot sequential suzuki-miyaura biaryl synthesis

Wing Kin Chow; Chau Ming So; Chak Po Lau; Fuk Yee Kwong

doi:10.1002/chem.201100361

Palladium-catalyzed borylation of aryl mesylates and tosylates and their applications in one-pot sequential suzuki-miyaura biaryl synthesis

Wing Kin Chow, Chau Ming So, Chak Po Lau, Fuk Yee Kwong

Research output: Journal article publication › Journal article › Academic research › peer-review

61 Citations (Scopus)

Abstract

Top of the one-pots! The first palladium-catalyzed borylation of aryl tosylates and mesylates is described. The reaction conditions are mild and provide excellent functional-group compatibility (e.g., R=CN, CHO, COOMe, C(O)R, NH2, or NH-indole; see scheme). Pd/MeO-CM-phos allows one-pot sequential reactions in the preparation of unsymmetrical biaryls.

Original language	English
Pages (from-to)	6913-6917
Number of pages	5
Journal	Chemistry - A European Journal
Volume	17
Issue number	25
DOIs	https://doi.org/10.1002/chem.201100361
Publication status	Published - 14 Jun 2011

Keywords

biaryls
borylation
cross-coupling
palladium
phosphine
tosylates

ASJC Scopus subject areas

Chemistry(all)

More information

10.1002/chem.201100361

Cite this

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abstract = "Top of the one-pots! The first palladium-catalyzed borylation of aryl tosylates and mesylates is described. The reaction conditions are mild and provide excellent functional-group compatibility (e.g., R=CN, CHO, COOMe, C(O)R, NH2, or NH-indole; see scheme). Pd/MeO-CM-phos allows one-pot sequential reactions in the preparation of unsymmetrical biaryls.",

keywords = "biaryls, borylation, cross-coupling, palladium, phosphine, tosylates",

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Palladium-catalyzed borylation of aryl mesylates and tosylates and their applications in one-pot sequential suzuki-miyaura biaryl synthesis. / Chow, Wing Kin; So, Chau Ming; Lau, Chak Po et al.

In: Chemistry - A European Journal, Vol. 17, No. 25, 14.06.2011, p. 6913-6917.

Research output: Journal article publication › Journal article › Academic research › peer-review

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AU - Kwong, Fuk Yee

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Y1 - 2011/6/14

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AB - Top of the one-pots! The first palladium-catalyzed borylation of aryl tosylates and mesylates is described. The reaction conditions are mild and provide excellent functional-group compatibility (e.g., R=CN, CHO, COOMe, C(O)R, NH2, or NH-indole; see scheme). Pd/MeO-CM-phos allows one-pot sequential reactions in the preparation of unsymmetrical biaryls.

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KW - borylation

KW - cross-coupling

KW - palladium

KW - phosphine

KW - tosylates

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JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

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Palladium-catalyzed borylation of aryl mesylates and tosylates and their applications in one-pot sequential suzuki-miyaura biaryl synthesis

Abstract

Keywords

ASJC Scopus subject areas

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