Palladium-catalyzed borylation of aryl mesylates and tosylates and their applications in one-pot sequential suzuki-miyaura biaryl synthesis

Wing Kin Chow, Chau Ming So, Chak Po Lau, Fuk Yee Kwong

Research output: Journal article publicationJournal articleAcademic researchpeer-review

54 Citations (Scopus)

Abstract

Top of the one-pots! The first palladium-catalyzed borylation of aryl tosylates and mesylates is described. The reaction conditions are mild and provide excellent functional-group compatibility (e.g., R=CN, CHO, COOMe, C(O)R, NH2, or NH-indole; see scheme). Pd/MeO-CM-phos allows one-pot sequential reactions in the preparation of unsymmetrical biaryls.
Original languageEnglish
Pages (from-to)6913-6917
Number of pages5
JournalChemistry - A European Journal
Volume17
Issue number25
DOIs
Publication statusPublished - 14 Jun 2011

Keywords

  • biaryls
  • borylation
  • cross-coupling
  • palladium
  • phosphine
  • tosylates

ASJC Scopus subject areas

  • Chemistry(all)

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