Pain Symptoms in Optic Neuritis

Xiayin Yang; Xuefen Li; Mengying Lai; Jincui Wang; Shaoying Tan; Henry Ho-lung Chan

doi:10.3389/fpain.2022.865032

Pain Symptoms in Optic Neuritis

Xiayin Yang, Xuefen Li, Mengying Lai, Jincui Wang, Shaoying Tan (Corresponding Author), Henry Ho-lung Chan (Corresponding Author)

Research output: Journal article publication › Journal article › Academic research › peer-review

Abstract

Signs and symptoms of optic neuritis (ON), an autoimmune disorder of the central nervous system (CNS), differ between patients. Pain, which is commonly reported by ON patients, may be the major reason for some patients to visit the clinic. This article reviews the presence of pain related to ON with respect to underlying disorders, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein associated disease (MOGAD). The aim of this review is to provide an overview of pain symptoms in accordance with the context of various pathophysiological explanations, assist in differential diagnosis of ON patients, especially at the onset of disease, and make recommendations to aid physicians make decisions for follow up diagnostic examinations.

Original language	English
Article number	865302
Pages (from-to)	1-13
Number of pages	13
Journal	Frontiers in Pain Research
Volume	3
DOIs	https://doi.org/10.3389/fpain.2022.865032
Publication status	Published - 14 Apr 2022

Keywords

pain
optic neuritis
mechanism
treatment
multiple sclerosis
Neuromyelitis optica spectrum disorders
myelin oligodendrocyte glycoprotein associated disease

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10.3389/fpain.2022.865032

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title = "Pain Symptoms in Optic Neuritis",

abstract = "Signs and symptoms of optic neuritis (ON), an autoimmune disorder of the central nervous system (CNS), differ between patients. Pain, which is commonly reported by ON patients, may be the major reason for some patients to visit the clinic. This article reviews the presence of pain related to ON with respect to underlying disorders, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein associated disease (MOGAD). The aim of this review is to provide an overview of pain symptoms in accordance with the context of various pathophysiological explanations, assist in differential diagnosis of ON patients, especially at the onset of disease, and make recommendations to aid physicians make decisions for follow up diagnostic examinations.",

keywords = "pain, optic neuritis, mechanism, treatment, multiple sclerosis, Neuromyelitis optica spectrum disorders, myelin oligodendrocyte glycoprotein associated disease",

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AU - Yang, Xiayin

AU - Li, Xuefen

AU - Lai, Mengying

AU - Wang, Jincui

AU - Tan, Shaoying

AU - Chan, Henry Ho-lung

PY - 2022/4/14

Y1 - 2022/4/14

N2 - Signs and symptoms of optic neuritis (ON), an autoimmune disorder of the central nervous system (CNS), differ between patients. Pain, which is commonly reported by ON patients, may be the major reason for some patients to visit the clinic. This article reviews the presence of pain related to ON with respect to underlying disorders, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein associated disease (MOGAD). The aim of this review is to provide an overview of pain symptoms in accordance with the context of various pathophysiological explanations, assist in differential diagnosis of ON patients, especially at the onset of disease, and make recommendations to aid physicians make decisions for follow up diagnostic examinations.

AB - Signs and symptoms of optic neuritis (ON), an autoimmune disorder of the central nervous system (CNS), differ between patients. Pain, which is commonly reported by ON patients, may be the major reason for some patients to visit the clinic. This article reviews the presence of pain related to ON with respect to underlying disorders, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein associated disease (MOGAD). The aim of this review is to provide an overview of pain symptoms in accordance with the context of various pathophysiological explanations, assist in differential diagnosis of ON patients, especially at the onset of disease, and make recommendations to aid physicians make decisions for follow up diagnostic examinations.

KW - pain

KW - optic neuritis

KW - mechanism

KW - treatment

KW - multiple sclerosis

KW - Neuromyelitis optica spectrum disorders

KW - myelin oligodendrocyte glycoprotein associated disease

U2 - 10.3389/fpain.2022.865032

DO - 10.3389/fpain.2022.865032

M3 - Journal article

SN - 2673-561X

VL - 3

SP - 1

EP - 13

JO - Frontiers in Pain Research

JF - Frontiers in Pain Research

M1 - 865302

ER -

Pain Symptoms in Optic Neuritis

Abstract

Keywords

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