Organocatalyzed asymmetric synthesis of dihydrodibenzofurans based on a dienamine process

Zi Yu Wang; Wing Tak Wong; Dan Yang

doi:10.1021/ol402288y

Organocatalyzed asymmetric synthesis of dihydrodibenzofurans based on a dienamine process

Zi Yu Wang
, Wing Tak Wong
, Dan Yang

Research output: Journal article publication › Journal article › Academic research › peer-review

36 Citations (Scopus)

Abstract

The first organocatalyzed asymmetric method for the synthesis of dihydrodibenzofurans based on a dienamine process has been developed. This two-step protocol works with a broad range of substrates and delivers only the cis-diastereomer in good yield with up to 91% ee. The enantioenriched products have been transformed to highly functionalized and partially hydrogenated dibenzofurans in excellent diastereoselectivities.

Original language	English
Pages (from-to)	4980-4983
Number of pages	4
Journal	Organic Letters
Volume	15
Issue number	19
DOIs	https://doi.org/10.1021/ol402288y
Publication status	Published - 4 Oct 2013
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol402288y

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DO - 10.1021/ol402288y

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Organocatalyzed asymmetric synthesis of dihydrodibenzofurans based on a dienamine process

Abstract

ASJC Scopus subject areas

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