Organocatalyzed asymmetric synthesis of dihydrodibenzofurans based on a dienamine process

Zi Yu Wang, Wing Tak Wong, Dan Yang

Research output: Journal article publicationJournal articleAcademic researchpeer-review

30 Citations (Scopus)

Abstract

The first organocatalyzed asymmetric method for the synthesis of dihydrodibenzofurans based on a dienamine process has been developed. This two-step protocol works with a broad range of substrates and delivers only the cis-diastereomer in good yield with up to 91% ee. The enantioenriched products have been transformed to highly functionalized and partially hydrogenated dibenzofurans in excellent diastereoselectivities.
Original languageEnglish
Pages (from-to)4980-4983
Number of pages4
JournalOrganic Letters
Volume15
Issue number19
DOIs
Publication statusPublished - 4 Oct 2013
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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