Organic electrochemical transistor array for recording transepithelial ion transport of human airway epithelial cells

Chunlei Yao, Changyan Xie, Peng Lin, Feng Yan, Pingbo Huang, I. Ming Hsing

Research output: Journal article publicationJournal articleAcademic researchpeer-review

36 Citations (Scopus)

Abstract

An organic electrochemical transistor array is integrated with human airway epithelial cells. This integration provides a novel method to couple transepithelial ion transport with electrical current. Activation and inhibition of transepithelial ion transport are readily detected with excellent time resolution. The organic electrochemical transistor array serves as a promising platform for physiological studies and drug testing. KGaA, Weinheim.
Original languageEnglish
Pages (from-to)6575-6580
Number of pages6
JournalAdvanced Materials
Volume25
Issue number45
DOIs
Publication statusPublished - 3 Dec 2013

Keywords

  • cell biosensors
  • cystic fibrosis transmembrane conductance regulators
  • ion channels
  • organic electrochemical transistors
  • transepithelial ion transport

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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