Optofluidic spectrometer for microchip flow cytometry

W. Z. Song, L. A.G. Lin, A. Q. Liu, C. S. Lim, P. H. Yap

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

Abstract

A compact optofluidic spectrometer is demonstrated for the fluorescence detection of moving particles in a microfluidic chip. The object is excited within an integrated liquid-liquid waveguide and its fluorescence spectrum is recorded in real time with resolution of 10 nm. Three different types of fluorescence beads were tested and distinguished by this spectrometer. This micro-optical-fluidic-systems (MOFS) hold a promising new concept of the multi-color fluorescence detection in microchip flow cytometry. Besides the low cost and compact, it also bears the advantages of self-reference, high sensitivity, high speed and accuracy.

Original languageEnglish
Title of host publicationProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
EditorsJean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin
PublisherChemical and Biological Microsystems Society
Pages11-13
Number of pages3
ISBN (Electronic)9780979806407
Publication statusPublished - Apr 2007
Externally publishedYes
Event11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France
Duration: 7 Oct 200711 Oct 2007

Publication series

NameProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Conference

Conference11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
Country/TerritoryFrance
CityParis
Period7/10/0711/10/07

Keywords

  • Liquid-liquid waveguide
  • Microchip flow cytometry
  • Optofluidic
  • Spectrometer

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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