Oncogenic role of nucleophosmin/B23

Yat Ming Yung

Research output: Journal article publicationReview articleAcademic researchpeer-review

42 Citations (Scopus)


Nucleophosmin/B23 was first identified as a nucleolar protein expressed at higher levels in cancer cells compared to normal cells. Nucleophosmin/B23 has long been thus thought to have a role in tumor formation. With our efforts and others in the last 15 years, nucleophosmin/B23 has proven to have an oncogenic role. In this review, we provide evidence suggesting that nucleophosmin/B23 may be a crucial gene in regulation of cancer growth and discuss how nucleophosmin/B23 can contribute to tumorigenesis.
Original languageEnglish
Pages (from-to)285-293
Number of pages9
JournalChang Gung Medical Journal
Issue number4
Publication statusPublished - 1 Jul 2007
Externally publishedYes


  • Nucleolus
  • Nucleophosmin/B23
  • Tumorigenesis

ASJC Scopus subject areas

  • General Medicine


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