On-chip droplet enhanced fluorescence emission for low concentration protein measurement

Y. F. Yu, T. Bourouina, A. Q. Liu

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

Abstract

On-chip droplet enhanced fluorescence emission for low concentration protein measurement is presented in this paper. The system includes T-junction of microchannel for micro-droplet generation and two integrated optical fibers for excitation laser input and fluorescence detection. The excitation light is confined in the droplet by total internal reflection to increase the optical path length, which enhances the fluorescence emission. The on-chip droplet features higher stability and easier manipulation. The size of the droplet can be varied by changing the flow conditions. The intensity of the droplet enhanced fluorescence emission is much higher than the intensity of the free space fluorescence, which promises wide applications in biological detection and measurement.

Original languageEnglish
Title of host publicationTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
Pages1250-1252
Number of pages3
DOIs
Publication statusPublished - Jun 2009
Externally publishedYes
EventTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems - Denver, CO, United States
Duration: 21 Jun 200925 Jun 2009

Publication series

NameTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems

Conference

ConferenceTRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
Country/TerritoryUnited States
CityDenver, CO
Period21/06/0925/06/09

Keywords

  • Droplet
  • Fluorescence emission
  • Microfluidics
  • Microphotonicfluidic systems and optofluidics

ASJC Scopus subject areas

  • Hardware and Architecture
  • Electrical and Electronic Engineering

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