TY - GEN
T1 - Numerical study on the influence of microchannel's geometry on submicron particles separation using acoustophoresis
AU - Lai, Tsz Wai
AU - Fu, Sau Chung
AU - Chan, Ka Chung
AU - Chao, Christopher Yu Hang
AU - Law, Anthony Kwok Yung
N1 - Funding Information:
The work was supported by a Hong Kong Special Administrative Region (HKSAR) Government Collaborative Research Fund (CRF) project (no. C7025-16G), General Research Fund (GRF) project (no. 16207817 & 16206918)
Publisher Copyright:
© 2020 ASME.
PY - 2020
Y1 - 2020
N2 - Application of acoustophoresis to cell and particle separation in microchannel filled with fluid medium has been drawing increasing attention in many disciplines in the past decades due to its high precision and minimum damage to the matters of interest. Previous studies on particle separation often rely on the size-dependent feature of the acoustic radiation force (ARF), while the acoustic streaming effect (ASE) is a hurdle as the particle size goes down. Sub-micron particles circulate according to the streaming vortices and become inseparable from the particles settled on the pressure node. Instead of suppressing the ASE, this study intends to utilize the combined effect of ARF and ASE on sub-micron particle sorting by altering the microchannel's cross-sectional shapes. The roles of ARF and ASE on particles with 0.2um and 2um in radius in various crosssectional shapes are studied numerically. The studied geometries include 1. rectangular, 2. trapezoidal, and 3. triangular. The results show that changing the cross-sectional shapes affects the acoustic field's magnitude and distribution, the streaming patterns, the magnitude of streaming velocity, and the movement of sub-micron particles. In non-rectangular microchannel, submicron particles circulate towards and settle at the center of the streaming vortices. This phenomenon shows the potential to manipulate the streaming-dominant particles, thereby enhancing the acoustophoretic particle sorting performance.
AB - Application of acoustophoresis to cell and particle separation in microchannel filled with fluid medium has been drawing increasing attention in many disciplines in the past decades due to its high precision and minimum damage to the matters of interest. Previous studies on particle separation often rely on the size-dependent feature of the acoustic radiation force (ARF), while the acoustic streaming effect (ASE) is a hurdle as the particle size goes down. Sub-micron particles circulate according to the streaming vortices and become inseparable from the particles settled on the pressure node. Instead of suppressing the ASE, this study intends to utilize the combined effect of ARF and ASE on sub-micron particle sorting by altering the microchannel's cross-sectional shapes. The roles of ARF and ASE on particles with 0.2um and 2um in radius in various crosssectional shapes are studied numerically. The studied geometries include 1. rectangular, 2. trapezoidal, and 3. triangular. The results show that changing the cross-sectional shapes affects the acoustic field's magnitude and distribution, the streaming patterns, the magnitude of streaming velocity, and the movement of sub-micron particles. In non-rectangular microchannel, submicron particles circulate towards and settle at the center of the streaming vortices. This phenomenon shows the potential to manipulate the streaming-dominant particles, thereby enhancing the acoustophoretic particle sorting performance.
KW - Acoustophoretic particle sorting
KW - Microchannel's geometry
KW - Microfluidics
UR - http://www.scopus.com/inward/record.url?scp=85101293390&partnerID=8YFLogxK
U2 - 10.1115/IMECE2020-23571
DO - 10.1115/IMECE2020-23571
M3 - Conference article published in proceeding or book
AN - SCOPUS:85101293390
T3 - ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
BT - Acoustics, Vibration, and Phononics
PB - American Society of Mechanical Engineers(ASME)
T2 - ASME 2020 International Mechanical Engineering Congress and Exposition, IMECE 2020
Y2 - 16 November 2020 through 19 November 2020
ER -