Numerical investigation of the effect of blade geometry on blood trauma in a centrifugal blood pump

W.K. Chan, Y.W. Wong, Y. Ding, L.P. Chua, Ching Man Yu

Research output: Journal article publicationJournal articleAcademic researchpeer-review

36 Citations (Scopus)

Abstract

Fluid dynamic forces in centrifugal blood pump impellers are of key importance in destruction of red blood cells (RBCs) because high rotational speed leads to strong interaction between the impeller and the RBCs. In this paper, three-dimensional models of five different blade geometries are investigated numerically using the commercial software CFX-TASCflow, and the streaklines of RBCs are obtained using the Lagrangian particle tracking method. In reality, RBCs pass through the pump along complicated paths resulting in a highly irregular loading condition for each RBC. In order to enable the prediction of blood damage under the action of these complexloading conditions, a cumulative damage model for RBCs was adopted in this paper. The numerically simulated percent hemoglobin (%HB) released as RBCs traversed the impeller and volute was examined. It was observed that the residence time of particles in the blade passage is a critical factor in determining hemolytic effects. This, in turn, is a function of the blade geometry. In addition, it was observed that the volute profile is an important influence on the computed HB% released.
Original languageEnglish
Pages (from-to)785-793
Number of pages9
JournalArtificial Organs
Volume26
Issue number9
DOIs
Publication statusPublished - 23 Sep 2002
Externally publishedYes

Keywords

  • Blood trauma
  • Centrifugal blood pump
  • Computational fluid dynamics
  • Numerical simulation

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering

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