Novel core-shell nanoparticles and their application in high-capacity immobilization of enzymes

Xuepu Mao; Jinfeng Huang; Man Fai Leung; Zhiyun Du; Lin Ma; Zhishu Huang; Pei Li; Lianquan Gu

doi:10.1385/ABAB:135:3:229

Novel core-shell nanoparticles and their application in high-capacity immobilization of enzymes

Xuepu Mao, Jinfeng Huang, Man Fai Leung, Zhiyun Du, Lin Ma, Zhishu Huang, Pei Li, Lianquan Gu

Research output: Journal article publication › Journal article › Academic research › peer-review

25 Citations (Scopus)

Abstract

Novel core-shell nanoparticles consisting of poly(methyl methacrylate) (PMMA) cores coated with synthetic polymer and biopolymer (polyethyleneimine, chitosan, and casein) shells were synthesized via direct graft copolymerization of methyl methacrylate from hydrophilic polymers in the absence of surfactant. Average hydrodynamic diameters of the nanoparticles ranged from 163 to 263 nm. High-capacity (up to 530 mg/g) immobilizations of enzymes and high-activity retained percentage (Espe) (up to 90%) were achieved.

Original language	English
Pages (from-to)	229-246
Number of pages	18
Journal	Applied Biochemistry and Biotechnology
Volume	135
Issue number	3
DOIs	https://doi.org/10.1385/ABAB:135:3:229
Publication status	Published - 1 Dec 2006

Keywords

Core shell
Immobilized cellulase
Nanoparticles
Poly(methyl methacrylate)

ASJC Scopus subject areas

Biotechnology
Bioengineering
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology

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10.1385/ABAB:135:3:229

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title = "Novel core-shell nanoparticles and their application in high-capacity immobilization of enzymes",

abstract = "Novel core-shell nanoparticles consisting of poly(methyl methacrylate) (PMMA) cores coated with synthetic polymer and biopolymer (polyethyleneimine, chitosan, and casein) shells were synthesized via direct graft copolymerization of methyl methacrylate from hydrophilic polymers in the absence of surfactant. Average hydrodynamic diameters of the nanoparticles ranged from 163 to 263 nm. High-capacity (up to 530 mg/g) immobilizations of enzymes and high-activity retained percentage (Espe) (up to 90%) were achieved.",

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AU - Mao, Xuepu

AU - Huang, Jinfeng

AU - Leung, Man Fai

AU - Du, Zhiyun

AU - Ma, Lin

AU - Huang, Zhishu

AU - Li, Pei

AU - Gu, Lianquan

PY - 2006/12/1

Y1 - 2006/12/1

N2 - Novel core-shell nanoparticles consisting of poly(methyl methacrylate) (PMMA) cores coated with synthetic polymer and biopolymer (polyethyleneimine, chitosan, and casein) shells were synthesized via direct graft copolymerization of methyl methacrylate from hydrophilic polymers in the absence of surfactant. Average hydrodynamic diameters of the nanoparticles ranged from 163 to 263 nm. High-capacity (up to 530 mg/g) immobilizations of enzymes and high-activity retained percentage (Espe) (up to 90%) were achieved.

AB - Novel core-shell nanoparticles consisting of poly(methyl methacrylate) (PMMA) cores coated with synthetic polymer and biopolymer (polyethyleneimine, chitosan, and casein) shells were synthesized via direct graft copolymerization of methyl methacrylate from hydrophilic polymers in the absence of surfactant. Average hydrodynamic diameters of the nanoparticles ranged from 163 to 263 nm. High-capacity (up to 530 mg/g) immobilizations of enzymes and high-activity retained percentage (Espe) (up to 90%) were achieved.

KW - Core shell

KW - Immobilized cellulase

KW - Nanoparticles

KW - Poly(methyl methacrylate)

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U2 - 10.1385/ABAB:135:3:229

DO - 10.1385/ABAB:135:3:229

M3 - Journal article

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VL - 135

SP - 229

EP - 246

JO - Applied Biochemistry and Biotechnology

JF - Applied Biochemistry and Biotechnology

IS - 3

ER -

Novel core-shell nanoparticles and their application in high-capacity immobilization of enzymes

Abstract

Keywords

ASJC Scopus subject areas

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